| HUANG Li-qiong,SUN Zhi-juan,ZHAO Yong-cheng,WANG Ji-xian.Transfer of ERR for radiation-related leukemia from Japanese population to Chinese population[J].Chinese Journal of Radiological Medicine and Protection,2011,31(4):474-477 |
| Transfer of ERR for radiation-related leukemia from Japanese population to Chinese population |
| Received:November 29, 2010 |
| DOI：10.3760/cma.j.issn.0254-5098.2011.04.027 |
| KeyWords:Excess relative risk Risk transfer model Japanese atomic bomb survivors Life span study Leukemia |
| FundProject: |
| Author Name | Affiliation | E-mail | | HUANG Li-qiong | Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, 300192 Tianjin, China | | | SUN Zhi-juan | Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, 300192 Tianjin, China | | | ZHAO Yong-cheng | Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, 300192 Tianjin, China | zhaoyc60@yahoo.com.cn | | WANG Ji-xian | Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, 300192 Tianjin, China | |
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| Abstract:: |
| Objective To establish a transfer model for excess relative risk (ERR) for radiation-related leukemia from Japanese population to Chinese population. Methods Combined ERR of several subtypes of leukemia published in 1994, with the corresponding leukemia baseline incidence rates obtained from Cancer Incidence in Five Continents Vol. IX (CI5-IX) for Japanese population and Chinese population, a weighted risk transfer model was employed between an additive model and a multiplicative model, to execute ERR transfer. Results A range of weighing factors was proposed for risk transfer models: weighing factor was 0.4 for male and 0.3 for female, acute lymphoblastic leukemia, acute myeloid leukemia and chronic myeloid leukemia. The uncertainty for ERR transfer was characterized by lognormal distribution. Conclusions Based on the difference of baseline incidence rate for subtypes of leukemia between Japanese population and Chinese population, the transfer model and these weighing factors discussed in the present study could be applicable to transfer ERR for radiation-related leukemia from Japanese population to Chinese population. |
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