ZHOU Ling,YIN Zhi-hua,HAN Zhong-hui,ZHOU Bao-sen,LIU Bao-chen,CUI Yong,GUO Jun-qiao,WU Wei,GUO Kun,LI Yong-jiu,CHEN Zhong-xing,ZHANG Qiang,QIAO Bao-jun,SU Xu.Birth defects in perinatal infants in areas contiguous to Hongyanhe Nuclear Power Plant before its normal operation[J].Chinese Journal of Radiological Medicine and Protection,2011,31(2):149-152
Birth defects in perinatal infants in areas contiguous to Hongyanhe Nuclear Power Plant before its normal operation
Received:December 01, 2010  
DOI:10.3760/cma.j.issn.0254-5098.2011.02.008
KeyWords:Nuclear power plant  Birth defects  Perinatal infant
FundProject:卫生行业科研专项(200802018)
Author NameAffiliation
ZHOU Ling Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
YIN Zhi-hua Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
HAN Zhong-hui Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
ZHOU Bao-sen Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
LIU Bao-chen Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
CUI Yong Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
GUO Jun-qiao Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
WU Wei Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
GUO Kun Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
LI Yong-jiu Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
CHEN Zhong-xing Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
ZHANG Qiang Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
QIAO Bao-jun Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
SU Xu Department of Epidemiology, School of Public Health, China Medical University, Shenyang 110001,China 
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Abstract::
      Objective To understand the status of birth defects among the perinatal infants in the areas contiguous to Hongyanhe nuclear power plant before its normal operation, so as to provide background information for the evaluation of the impact of nuclear power plant on birth defects. Methods From 1 October 1995 to 30 September 2009 the midwifery units at second class and above of Wafangdian City were asked to be in charge of recording the birth defects among the perinatal infants born during this period within the range of 50 km around the Hongyanhe nuclear power plant. Results The total number of birth defects was 697, and the maternal number was 83 779. The average defect rate was 83.20/104. There were significant differences in the birth defect rate among different years (χ2=39.54, P <0.05), however, without linear trend therein, and among the survey areas(χ2=15.36, P <0.05) as well. The top five birth defects were congenital heart disease (148 cases), cleft lip with cleft palate (67 cases), congenital hydrocephalus (63 cases), and spina bifida (37 cases) and cleft lip (36 cases). Conclusions The birth defect rate within the range of 50 km around the Hongyanhe nuclear power plant is lower than that of the region of Liaoning Province and the national rate of birth defects.
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