| HUO Jun-jie,QIAO Xue-ying,ZHOU Zhi-guo,WAN Xin,SONG Yu-zhi,CAO Yan-kun,GAO Xian-shu.Evaluation of respiration-induced dosimetric variance in three-dimensional conformal radiotherapy (3DCRT) for mid-thoracic esophageal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2010,30(6):714-717 |
| Evaluation of respiration-induced dosimetric variance in three-dimensional conformal radiotherapy (3DCRT) for mid-thoracic esophageal carcinoma |
| Received:January 06, 2010 |
| DOI： |
| KeyWords:Mid-thoracic esophageal carcinoma 3D-conformal radiotherapy Respiratory movement Dosimetry |
| FundProject:河北省卫生厅医学科学研究重点课题(07290);河北省普通高校强势特色学科项目(2005-52) |
| Author Name | Affiliation | E-mail | | HUO Jun-jie | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | QIAO Xue-ying | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | xueying_qiao@yahoo.com.cn | | ZHOU Zhi-guo | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | WAN Xin | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | SONG Yu-zhi | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | CAO Yan-kun | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | GAO Xian-shu | 北京大学第一医院放疗科 | |
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| Abstract:: |
| Objective To evaluate the respiration-induced dosimetric variance in 3DCRT for mid-thoracic esophageal carcinoma, in order to guide the radiation oncologist to choose the expansion margin.Methods Ten patients with mid-thoracic esophageal carcinoma were scanned by multi-spiral CT simulator respectively in free breathing (FB), breath-hold after normal inspiration and expiration (IBH and EBH) with the same scanning range. Then the CT images of three series were transferred to the treatment planning system. The target volume was outlined following the same standard. Plan1 was designed in the images of FB and transported completely to the images of IBH and EBH as Plan2 and Plan3 respectively to observe the dosimetric variance in target volume.Results For GTV, there was a statistical difference only in V100 of the three plans (H =6.423, P =0.040) and no significant difference was found in other indexes. For CTV, the V100 and V95 were better in Plan1 (F =3.992, P =0.030; H =9.920, P =0.007) and no significant difference was found in other indexes. While for PTV, the Dmin, V100 and V95 was better in Plan1 (F =3.677, P =0.039; F =4.539, P =0.020; H =6.846, P =0.033) and no significant difference was found in other indexes. There were no significant differences in all the indexes for the spinal cord and lung in the three plans.Conclusions The change in dose distribution was not so much with the standard expansion. It can meet the needs of clinical treatment. |
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