| ZHANG Hui-juan,ZHOU Gui-xia,DAI Xiang-kun,et al.Dosimetric comparison between helical tomotherapy and step-and-shoot intensity modulated radiation therapy for cervix carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2010,30(3):317-319 |
| Dosimetric comparison between helical tomotherapy and step-and-shoot intensity modulated radiation therapy for cervix carcinoma |
| Received:August 17, 2009 |
| DOI：10.3760/cma.j.issn.0254-5098.2010.03.023作者单位:100853 北京,中国人民解放军总医院放射治疗科 |
| KeyWords:Post-operative cervix cancer/radiotherapy Helical tomotherapy Intensity modulated radiotherapy Dosimetry |
| FundProject: |
| Author Name | Affiliation | | ZHANG Hui-juan | Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100853, China | | ZHOU Gui-xia | Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100853, China | | DAI Xiang-kun | Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100853, China | | XIE Chuan-bin | Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100853, China | | XU Shou-ping | Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100853, China | | JU Zhong-jian | Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100853, China | | GONG Han-shun | Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100853, China |
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| Abstract:: |
| Objective To compare the dosimetric characteristics of helical tomotherapy (HT) and step-and-shoot intensity modulated radiotherapy (IMRT) for post-operative cervix cancer patients.Methods Ten patients with post-operative cervix cancer were enrolled in this study. HT and IMRT plans were developed for each patient. The dose distributions of the targets, organs at risk (OARs), CI and HI were analyzed and compared. The prescribed dose was 60 Gy/25f for CTV1, 50 Gy/25f for CTV2. The iso-dose line of 50 Gy was used.Results The homogeneity indexes (HI) (0.94±0.03),conformity index(CI) (1.28±0.02) inHT group were better than in IMRT group(0.85±0.01 and 1.36±0.03),respectively (t =5.12,-6.34, P<0.001). The Dmean of PTV in HT group(51.77Gy)was lower than that in IMRT group(54.53Gy)(t =-8.01, P<0.05). The Dmax,Dmean,V30,V40 and V50 of bladder、rectum and small bowel were lower in HT group than those in IMRT group. The Dmax,Dmean,V30 and V40 of right and left femoral head were lower in HT group than those in IMRT group.ConclusionHelical tomotherapy treatment plan has a better homogeneity, steeper dose gradient, and a better protection for organs at risk. |
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