| ZHOU Gui-xia,DAI Xiang-kun,XU Shou-ping,JU Zhong-jian,GONG Han-shun,XIE Chuan-bin,DU Lei.Dosimetric study of three different kinds of radiotherapy techniqueforpost-operativebreastcancer[J].Chinese Journal of Radiological Medicine and Protection,2010,30(3):314-316 |
| Dosimetric study of three different kinds of radiotherapy techniqueforpost-operativebreastcancer |
| Received:August 14, 2009 |
| DOI：10.3760/cma.j.issn.0254-5098.2010.03.022作者单位: 100853 北京,中国人民解放军总医院放射治疗科 |
| KeyWords:Chest wall irradiation Helical tomotherapy Intensity-modulated radiation therapy Three-dimensional conformal radiation therapy |
| FundProject: |
| Author Name | Affiliation | | ZHOU Gui-xia | Department of Radiation Oncology, Chinese PLA General Hospital, Beijing 100853, China | | DAI Xiang-kun | Department of Radiation Oncology, Chinese PLA General Hospital, Beijing 100853, China | | XU Shou-ping | Department of Radiation Oncology, Chinese PLA General Hospital, Beijing 100853, China | | JU Zhong-jian | Department of Radiation Oncology, Chinese PLA General Hospital, Beijing 100853, China | | GONG Han-shun | Department of Radiation Oncology, Chinese PLA General Hospital, Beijing 100853, China | | XIE Chuan-bin | Department of Radiation Oncology, Chinese PLA General Hospital, Beijing 100853, China | | DU Lei | Department of Radiation Oncology, Chinese PLA General Hospital, Beijing 100853, China |
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| Abstract:: |
| Objective To investigate the dosimetric characteristics of helical tomotherapy (HT),intensity-modulated radiation therapy (IMRT) and three-dimensional conformal radiation therapy (3D- CRT) for the post-operative breast cancer as well as their comparison in protecting the normal tissues.Methods The CT images of 10 postoperative patients with early stage breast cancer were transferRed into HT and IMRT and 3D- CRT planning system respectively after the target region and normal tissues were drawn out with the same doctor. Each prescribed dose for three kinds of plans was 50 Gy/25 fractions. Inrradiation doses and volume at heart and double lungs as well as conformity index(CI) and homogeneity index(HI) were evaluated.Results The PTV volume of prescribed target dose of 95% and 100% in HT, IMRT and 3D-CRT groups were 99.13% and 95.87%, 97.80% and 94.05%, 96.37% and 87.29%, respectively.The CI and HI in HT, IMRT and 3D- CRT groups were 0.80±0.10 and 1.09±0.03, 0.65±0.07 and 1.14±0.02, 0.40±0.08 and 1.17±0.04, respectively V5, V10and V20 of the heart were the lowest at 3D-CRT than HT and IMRT. V5 of the diseased lung was the lowest at 3D- CRT compared to HT and IMRT.V5 and V10of the healthy lung were the lowest at 3D-CRT compared to other groups.Conclusions Compared with IMRT and 3D- CRT, HT technique in treating breast cancer had the best conformity index and homogeneity index as well as steeper dose gradient. Irradiated doses and volume at the heart was the lowest at 3D- CRT and the highest at IMRT. Irradiated doses and volume of the heart and healthy lung as well as the diseased lung were the lowest at 3D- CRT compared to HT and IMRT groups. |
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