| HUO Jun-jie,QIAO Xue-ying,CAO Yan-kun,ZHOU Zhi-guo,SONG Yu-zhi,CHI Zi-feng,LIU Xin,WANG Jing.Evaluation of respiration-induced target volume motion in three-dimensional conformal radiotherapy (3D-CRT) for mid-thoracic esophageal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2010,30(3):295-298 |
| Evaluation of respiration-induced target volume motion in three-dimensional conformal radiotherapy (3D-CRT) for mid-thoracic esophageal carcinoma |
| Received:July 27, 2009 |
| DOI：10.3760/cma.j.issn.0254-5098.2010.03.017 |
| KeyWords:Mid-thoracic esophageal carcinoma 3D-conformal radiotherapy Respiratory movement Target volume motion |
| FundProject:河北省卫生厅医学科学研究重点课题(07290);河北省普通高校强势特色学科资助项目(2005-52) |
| Author Name | Affiliation | E-mail | | HUO Jun-jie | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | QIAO Xue-ying | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | xueying_qiao@yahoo.com.cn | | CAO Yan-kun | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | ZHOU Zhi-guo | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | SONG Yu-zhi | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | CHI Zi-feng | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | LIU Xin | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | | | WANG Jing | Department of Radiation Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China | |
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| Abstract:: |
| Objective To evaluate the respiration-induced target volume motion in 3D-CRT for mid-thoracic esophageal carcinoma in order to guide the radiation oncologist to choose the expansion margin for ITV. Methods Ten patients with mid-thoracic esophageal carcinoma were scanned by multi-spiral CT simulator respectively in free breathing (FB), breath-hold after normal inspiration and expiration (IBH and EBH) with the same scanning range. Then the CT images of three series were transferred to the treatment planning system. The target volume was outlined following the same standard. The motion of the center point of GTV, the center point of each slice of GTV and the edge of the GTV in selected slice were measured respectively to obtain the comprehensive value of GTV motion, in order to find the appropriate IM value according to the 95% confidence interval of the GTV motion. Results 1 The GTV motion between IBH and EBH was (0.19±0.16) cm in the left-right direction, (0.54±0.19) cm in the cranial and caudal direction, and (0.16±0.14) cm in anterior-posterior directions for the center of GTV,. For the center point of each slice of GTV . they were (0.19±0.15) cm, (0.54±0.16) cm, (0.16±0.13) cm in three directions above, respectively. For the edge of the GTV in selected slice, they were (0.26±0.19) cm, (0.54±0.18) cm, (0.24±0.19) cm, respectively. The comprehensive value of GTV motion between IBH and EBH was (0.23±0.17) cm, (0.54±0.17) cm, (0.21±0.17) cm, respectively. The 95% confidence interval was 0.21-0.25 cm, 0.53-0.56 cm and 0.19-0.22 cm in three directions. 2The direction of GTV motion: No motion was noticed in 8.2%, while 73.3% to the right side and 18.5% to the left side in the left-right direction when IBH were compared with EBH. 100% were moved to caudal in the the cranial and caudal direction ［(0.54±0.17) cm］. In the anterior-posterior direction, no motion was noticed in 8.2%, while 16.6% to the posterior and 75.2% to the anterior when IBH were compared with EBH. 3The GTV motion was correlated with the variance of lung volumes in IBH-EBH (r=0.683, P=0.032) and not with GTV volume and length. Conclusions Respiration can induce target volume motion in 3DCRT for mid-thoracic esophageal carcinoma. Compared to EBH, the GTV tends to move to the caudal, the anterior and the right side in IBH. |
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