| ZHENG Ya-qin,XING Xiao-fen,XING Yu-rong,GUO Rui-song.Beam design in cervical cancer treatment with intensity-modulated radiation therapy[J].Chinese Journal of Radiological Medicine and Protection,2010,30(2):191-194 |
| Beam design in cervical cancer treatment with intensity-modulated radiation therapy |
| Received:July 22, 2009 |
| DOI： |
| KeyWords:Cervical neoplasms Intensity-modulated radiation therapy Dosimetry |
| FundProject: |
| Author Name | Affiliation | | ZHENG Ya-qin | Department of Radiation Oncology, Shanxi Cancer Hospital, Taiyuan 030013, China | | XING Xiao-fen | Department of Radiation Oncology, Shanxi Cancer Hospital, Taiyuan 030013, China | | XING Yu-rong | Department of Radiation Oncology, Shanxi Cancer Hospital, Taiyuan 030013, China | | GUO Rui-song | Department of Radiation Oncology, Shanxi Cancer Hospital, Taiyuan 030013, China |
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| Abstract:: |
| Objective To find the optimal beam arrangement for clinical cervical cancer treatment with intensity modulated radiation therapy(IMRT) technique through comparison between different beam arrangements.Methods Six IMRT plans were designed for 10 patients with cervical cancer. The prescribed dose was 46 Gy, while the fractionated dose was 2 Gy, and 5,7,9 equispaced beams were applied. The initial beam angle degrees were 0 and 180. The terms of target coverage, target dose uniformity, and target conformability were calculated and compared.Results The target conformabilities between 7 and 9-beam plans were identical, and dose uniformity between the two angles beams was the best in 7-beam plan. The target coverage was satisfactory in 5-beam plan, but the dose uniformity and target conformability in it were inferior to those in 7 and 9-beam plans. The dose on normal tissues in 9-beam plan was not less than that in 5-beam plans, but the treatment was prolonged due to the increased segments and monitor units (MU).Conclusions Considering the physical and biological factors during the cervical cancer treatment with IMRT, 7-beam plan would be the best choice for the beam design. |
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