| LU Jie,WU Zhao-xia,ZHANG Gui-fang,BAI Tong,FAN Ting-yong.Dosimetric comparison of three-dimensional conformal and intensity modulated radiotherapy in brain glioma[J].Chinese Journal of Radiological Medicine and Protection,2009,29(5):499-501,534 |
| Dosimetric comparison of three-dimensional conformal and intensity modulated radiotherapy in brain glioma |
| Received:January 04, 2009 |
| DOI： |
| KeyWords:Brain glioma Three-dimensional conformal radiotherapy Intensity modulated radiation therapy Dosimetry |
| FundProject:山东省科技攻关项目(2007GG20002030) |
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| Abstract:: |
| Objective To investigate the dosimetry advantages of intensity modulated radiotherapy(IMRT)of brain glioma compared with that of three-dimensional conformal radiotherapy (3D CRT). Methods Ten patients with brain glioma were enrolled in this study. Three-dimensional conformal and intensity modulated radiotherapy plans were performed for each patient. The dose distributions of target volume and normal tissues, conformal index (CI) and heterogeneous index (HI) were analyzed using the dose-volume histogram (DVH).The prescription dose was 60 Gy in 30 fractions. Results IMRT plans decrease the maximum dose and volume of brainstem, mean dose of affected side parotid and maximum dose of spinal-cord. The CI for PTV of IMRT was superior to that of 3D CRT, the HI for PTV has no statistical significance of the two model plans. Conclusions IMRT plans can obviously decrease the dose and volume of brainstem.IMRT is a potential method in the treatment of brain glioma, and dose escalation was possible in patients with brain glioma. |
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