| ZHU Li-hong,XU Bo,WU Hao,et al.Comparing of dose distribution between intensity-modulated radiotherapy simultaneous integrated boost and conventional radiotherapy for cervical cancer patients[J].Chinese Journal of Radiological Medicine and Protection,2009,29(4):405-409 |
| Comparing of dose distribution between intensity-modulated radiotherapy simultaneous integrated boost and conventional radiotherapy for cervical cancer patients |
| Received:February 27, 2009 |
| DOI： |
| KeyWords:Cervical neoplasms Intensity-modulated radiotherapy simultaneous integrated boost Conventional radiotherapy Dose distribution |
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| Abstract:: |
| Objective To assess the feasibility of applying intensity-modulated radiotherapy (IMRT) simultaneous integrated boost (SIB) to replace conventional radiotherapy (CR) plus brachytherapy of whole pelvis in locally advanced cervical cancer (LACC). Methods Five LACC patients based difference position of uterus were chosen and worked out CR and IMRT SIB plans respectively. Dose distributions were compared between IMRT SIB and CR. Results When uterus was in ante-, neutral-, retro-position and deviation respectively, IMRT SIB could provide enough and homogeneous dose distribution for target volume and reduce irradiated volumes and doses for organs at risk (recta, bladder and small intestine) than CR. The doses of the A, B, and fundus of uterus were higher in IMRT SIB than CR. However, in case of small intestine was close to or encircled the uterus, the targets volume dose would be inadequacy. Conclusions LACC IMRT SIB's dose distribution is better than CR (except excess ante-position) and may help to treat those patients who couldnt be suitable with brachytherapy. |
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