SUN Tao,LU Jie,YIN Yong,LIU Tong-hai,CHEN Jin-hu,LIN Xiu-tong,ZHU Jian,BAI Tong,LIU Bo.Comparison of forward and inverse intensity modulation radiotherapy planning for breast cancer after breast-conservative surgery[J].Chinese Journal of Radiological Medicine and Protection,2009,29(4):401-404
Comparison of forward and inverse intensity modulation radiotherapy planning for breast cancer after breast-conservative surgery
Received:April 24, 2009  
DOI:
KeyWords:Breast neoplasm  Breast-conservative surgery  Forward intensity-modulated radiotherapy  Inverse intensity-modulated radiotherapy
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Author NameAffiliationE-mail
SUN Tao Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China  
LU Jie Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China  
YIN Yong Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China yinyongsd@yahoo.com.cn 
LIU Tong-hai Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China  
CHEN Jin-hu Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China  
LIN Xiu-tong Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China  
ZHU Jian Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China  
BAI Tong Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China  
LIU Bo Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China  
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Abstract::
      Objective To compare the dosimetric difference inforwardintensity modulationradiotherapy(fIMRT) and inverse IMRT (iIMRT) planning for breast cancer.Methods Six patients received radiotherapyalone after left breast-conserving surgery were selected.For each patient, two treatment plans (fI MRT andiI MRT) were designed with Pinnacle37.4f.In each plan, the volume of PTV received prescription dose was notless than 95%.The dosi metric parameters were assessed with dose volume histograms in planning target volume(PTV) and organ of around risk (OAR). Results of fIMRT and iIMRT plans, the PTV average confor malindex were (0.67±0.06) and (0.66±0.06) (t=2.423, P>0.05), average homogeneity index were(28.2±6.0)% and (26.1±6.8)% (t=2.164, P>0.05); the volume of left lung received 20 Gy (V20)were (18.7±3.3)% and (17.0±2.8)% (t=5.087, P<0.05), and V30of left lung were (15.5±3.0)% and (14.0±2.6)% (t=7.272, P<0.05); V30of heart were (4.1±3.1)% and (3.5±2.5)% (t=1.916, P>0.05); the total monitor units were (262±5) MU and (308±14) MU (t=7.515, P<0.05).Conclusions There were no significant differences of CI, HI, and V30of heart between fIMRT and iIMRT.Because of fewer MUs, fI MRT plan could reduce the machine abrasion and treatment ti me, but V20 and V30 of left lung are higher significantly than iI MRT plan.
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