| SHEN Jie,ZHANG Fu-quan,QIU Jie,YANG Bo,PANG Ting-tian,XU Yan-zhen.Dosimetric comparison of conventional and three-dimensional radiotherapy techniques for limited-stage small cell lung cancer[J].Chinese Journal of Radiological Medicine and Protection,2009,29(4):397-400 |
| Dosimetric comparison of conventional and three-dimensional radiotherapy techniques for limited-stage small cell lung cancer |
| Received:April 24, 2009 |
| DOI： |
| KeyWords:Limited-stage small cell lung cancer Three dimensional conformal radiotherapy Conventional radiotherapy Dose volume histograms |
| FundProject:北京协和医院霍英东专项研究基金 |
| Author Name | Affiliation | E-mail | | SHEN Jie | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China | | | ZHANG Fu-quan | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China | zhangfuquan3@sina.com | | QIU Jie | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China | | | YANG Bo | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China | | | PANG Ting-tian | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China | | | XU Yan-zhen | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China | |
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| Abstract:: |
| Objective To compare the dosimetric difference in planning target volume (PTV) and organ at risk (OAR) with conventional and the three-dimensional treatment planning for limited-stage small cell lung cancer. Methods Ten patients with limited-stage small cell lung cancer were chosen in the present study. Two treatment planning were designed twice respectively with the Cadplan R 3.1.2 treatment planning system for each patient in two-course. The total radiation dose was 50 Gy. The dosimetric parameters were assessed with dose volume histograms in PTV and OAR. Results For the first course, the dose homogeneity indices(HI)of PTV1, conformal indices(CI) of PTV2, contralateral lung V30 and contralateral mean lung dose in the three-dimensional treatment planning were better than that in the conventional treatment planning. For the second course, the HI, CI and mean dose of PTV1, CI and mean dose of PTV2 in the three-dimensional treatment planning were better than that in the conventional treatment planning. Conclusions By comparison with conventional treatment planning, the three-dimensional conformal treatment planning could meet the demands of dosimetric requirements well for limited-stage small cell lung cancer with three-dimensional conformal radiotherapy, but with no significant dosimetric differences in the OAR. |
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