| HUANG Wei,QU Ya-qin,SONG Xiang-fu,et al.Effect of chest wall radiotherapy in different manners using tissue equivalent bolus on skin and lung of cavia cobayas[J].Chinese Journal of Radiological Medicine and Protection,2009,29(4):380-382 |
| Effect of chest wall radiotherapy in different manners using tissue equivalent bolus on skin and lung of cavia cobayas |
| Received:December 28, 2008 |
| DOI： |
| KeyWords:Cavia cobaya Chest wall radiotherapy Tissue equivalent bolus Skin Lung Biological effect |
| FundProject:吉林省科技厅白求恩基金资助项目(200705221) |
| Author Name | Affiliation | E-mail | | HUANG Wei | Department of Radiation Oncology, Second Hospital, Jilin University, Changchun 130021, China | | | QU Ya-qin | Department of Radiation Oncology, Second Hospital, Jilin University, Changchun 130021, China | quyaqin52@163.com | | SONG Xiang-fu | 吉林大学公共卫生学院 | | | LIU Shi-xin | 吉林省肿瘤医院 | | | JIANG Xin | Department of Radiation Oncology, Second Hospital, Jilin University, Changchun 130021, China | | | JIA Xiao-jing | Department of Radiation Oncology, Second Hospital, Jilin University, Changchun 130021, China | | | GUO He | 吉林大学中日联谊医院 | | | YANG Lei | 吉林省肿瘤医院 | |
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| Abstract:: |
| Objective To probe the influence of electron beam radiotherapy in different manners using different tissue equivalent boluses on skin and lung. Methods Adult female cavia cobayas were randomly divided into four groups as control group, full-time with bolus group, half-time with bolus group and without bolus group. Acute-irradiation animal models were established using electron beam in different manners with or without 0.5 cm tissue equivalent bolus. Pathological changes in lung, hair vesicle and fibroblast cell count were analyzed 40 days after irradiation. Results The radiation dermatitis in the group with bolus was slighter than that of the group without bolus, but the radiation pneumonia was reverse. With bolus, the radiation dermatitis of half-time group was slighter than that of full-time group. The injury repair of half-time group was more active than full-time group. Conclusions The treatment of half-time bolus could protect lung without serious skin complications. |
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