| ZHANG Xi,CHEN Shao-liang,YANG Xin-rong,LI Hai-qing,YUAN Qing-xi,ZHU Pei-ping,CHEN Yu,HUANG Wan-xia.A preliminary study of phase contrast X-ray imaging with synchrotron radiation[J].Chinese Journal of Radiological Medicine and Protection,2009,29(3):317-319 |
| A preliminary study of phase contrast X-ray imaging with synchrotron radiation |
| Received:August 01, 2008 |
| DOI：10.3760/cma.j.issn.0254-5098.2009.03.027 |
| KeyWords:Synchrotron radiation Phase contrast imaging Diffraction enhanced imaging Blood vessel X-rays |
| FundProject:国家自然科学基金(30471652) |
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| Abstract:: |
| Objective To investigate the mouse liver blood vessel images using phase contrast X-ray imaging with synchrotron radiation.Methods 6 female C57BL/6 mice were randomly divided into two groups, 3 mice in each group. In one group, livers excised after ligated arteries, veins and common bile duct. In another group, iodine infused via the portal vein and drained from inferior vena cave until all the blood in the portal veins and hepatic veins was displaced. After infusion, arteries, veins and common bile duct were ligated and livers were excised. ResultsBlood vessel images were clearly produced by diffraction enhanced imaging. This method can discriminate vessels down to about 40 μm in diameter without contrast agent. Using a contrasting agent more details could be produced. In one liver lobe, the entire branch of the portal vein could be clearly produced by one by one phase contrast image from the main axial blood vessels of liver lobe to the nine generation of branching. Conclusions Phase contrast imaging has the advantage of good contrast and high spatial resolution. |
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