| DUAN Yu-long,FAN Xiang-hui,SHI Zhong-zhou,et al.Clinical analysis of X-knife under fractionational stereotactic radiotherapy combine whole brain radioterapy for brain metastases tumor[J].Chinese Journal of Radiological Medicine and Protection,2009,29(3):286-287 |
| Clinical analysis of X-knife under fractionational stereotactic radiotherapy combine whole brain radioterapy for brain metastases tumor |
| Received:June 13, 2008 |
| DOI：10.3760/cma.j.issn.0254-5098.2009.03.012 |
| KeyWords:Neoplasm metastais Brain \ Stereotactic radiotherapy \ Whole brain radiotherapy \ Prognosis |
| FundProject: |
| Author Name | Affiliation | | DUAN Yu-long | The Second People Hospital of Pingdingshan, Henan Province, Pingdingshan 467000, China | | FAN Xiang-hui | The Second People Hospital of Pingdingshan, Henan Province, Pingdingshan 467000, China | | SHI Zhong-zhou | The Second People Hospital of Pingdingshan, Henan Province, Pingdingshan 467000, China | | ZHAO Cheng | The Second People Hospital of Pingdingshan, Henan Province, Pingdingshan 467000, China | | DING Chao-peng | The Second People Hospital of Pingdingshan, Henan Province, Pingdingshan 467000, China | | XIE Hong-quan | The Second People Hospital of Pingdingshan, Henan Province, Pingdingshan 467000, China | | ZHANG Xiao-li | The Second People Hospital of Pingdingshan, Henan Province, Pingdingshan 467000, China |
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| Abstract:: |
| Objective To evaluate efficiency of brain metastases tumor using X-knife under farctionational stereotactic radiotherapy (FSRT) combine with whole brain radiotherapy (WBRT).Methods Retrospective comparing 51 patients treated by FSRT plus WBRT (FSRT+WBRT group) with 35 patients treated by WBRT alone (WBRT group) on the effecting rate and survival rate.Results The completeness response rate was 49% and 26% (P<0.05) in FSRT+WBRT and WBRT groups, respectively. The effecting rate was 80% and 71% (P>0.05) in FSRT+WBRT and WBRT groups, respectively. The middle survival time was (11.0±1.5) months and (6.5+0.5) months (P<0.05) in FSRT+WBRT and WBRT groups, respectivley. The 0.5-,1.0- and 1.5-years survival rate was 63% and 41% (P>0.05), 51% and 23% (P>0.05) and 24% and 9% (P<0.05) in FSRT+WBRT and WBRT groups, respectively.Conclusions The method with FSRT plus WBRT in the treatment of brain metastases tumor is safe and relieved focal symptom of patients quickly with lesser injury on normal tissue and the survival time be prolonged,it has better therapeutic effects than WBRT alone for treating brain metastases tumor. |
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