| ZHANG Fu-li,ZHENG Ming-min,CHEN Jian-ping.Dosimetric comparison of three-dimensional conformal radiotherapy and simplified intensity-modulated radiotherapy for non-small cell lung cancer[J].Chinese Journal of Radiological Medicine and Protection,2009,29(3):283-285 |
| Dosimetric comparison of three-dimensional conformal radiotherapy and simplified intensity-modulated radiotherapy for non-small cell lung cancer |
| Received:June 26, 2008 |
| DOI：10.3760/cma.j.issn.0254-5098.2009.03.011 |
| KeyWords:Lung neoplasms Radiotherapy Three dimensional conformal Intensity modulated Dosimetry |
| FundProject:10.3760/cma.j.issn.0254-5098.2009.03.011 |
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| Abstract:: |
| Objective To compare dosimetric difference of treatment planning of three-dimensional conformal radiotherapy (3D-CRT) and simplified intensity-modulated radiotherapy (sIMRT) for non-small cell lung cancer (NSCLC).Methods Ten NSCLC patients treaded by radiotherapy were investigated. 3D-CRT and sIMRT plannings were designed for each patient. The prescribed dose was 60 Gy(2 Gy/f), the 95% of the planning target volume was received with this dose for each patient. The dose was computed with treatment planning system of ADAC Pinnacl using convolution/superposition algorithm. Two plans were compared according to the homogeneity index (HI) and conformity index (CI) of dosimetry in the planning target volume and the parameters of dose-volume histogram (DVH) in normal tissue. Results In the terms of HI and CI, sIMRT had slight vantages over 3D-CRT. In the terms of DVH, compared with 3D-CRT, mean lung dose, V5, V10 and V20 of sIMRT reduced by 14.81%, 17.88%, 19.15% and 27.78%, respectively. The dosimetric differences were not statistically significant between 3D-CRT and sIMRT in terms of esophagus, heart and spinal cord.Conclusions For NSCLC, sIMRT has some irreplaceable advantages over 3D-CRT and is worth spreading in clinical work. |
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