| XIONG Hua,CHEN Yuan,YU Shi-ying,ZHUANG Liang,LIU Fei,XIONG Hui-hua.Influence of belly board device and the distended bladder on dosimetric analysis and normal tissue complication in postoperative radiation therapy of rectal cancer[J].Chinese Journal of Radiological Medicine and Protection,2009,29(2):168-171 |
| Influence of belly board device and the distended bladder on dosimetric analysis and normal tissue complication in postoperative radiation therapy of rectal cancer |
| Received:March 11, 2008 |
| DOI：10.3760/cma.j.issn.0254-5098.2009.02.016 |
| KeyWords:Belly board device Small bowel injury Distended bladder |
| FundProject: |
| Author Name | Affiliation | | XIONG Hua | Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China | | CHEN Yuan | Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China | | YU Shi-ying | Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China | | ZHUANG Liang | Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China | | LIU Fei | Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China | | XIONG Hui-hua | Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China |
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| Abstract:: |
| Objective To evaluate the influence of belly board device and the distended bladder on the dose distribution of PTV and the dose-volume histograms(DVHs) of organs at risk(OARs) for postoperative radiation therapy of rectal cancer.Methods A total of 23 patients (8 and 15) with distended bladder receiving 3-field postoperative radiation therapy were dealed with or without a special belly board in the prone position. At the same time, 15 cases with belly board were scanned with empty bladder. The volume of irradiated small bowel was calculated for doses between 5-50 Gy at 5Gy intervals. With prescription dose in plan target volume (PTV) of 50 Gy, we compared the dose distribution, DVH of OARs, conformity index (CIPTV), the volume of irradiated small bowel and the acute toxicity under the condition of three different moulds.Results There was no significant difference in PTV's converge, DVHs of femoral head and CI among 3 moulds(P>0.05). With the belly board, the high-dose volume of irradiated small bowel (V20-V52.5) was significantly decreased(P<0.05), specially with distended bladder. However, the low dose volume(V5-V15) was slightly increased. The bladder distension significantly decreases the volumes of the irradiated small bowel at dose levels from 15-52.5 Gy(P<0.05). Furthermore, the mean volume (V5-V30)of irradiated small bowel differed significantly between patients experiencing Grade 0-1 and ≥2 diarrhea(P<0.05).Conclusion The combination of belly board and distended bladder was more effectively to reduce the irradiated small bowel volume among 3 moulds, so as to minimized acute diarrhea toxicity. |
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