QIN Ling,YANG Xiao-ye,LI Ling,et al.Telephone information-memory-concentration test used in evaluating cognitive function of patients with nasopharyngeal carcinoma after radiotherapy[J].Chinese Journal of Radiological Medicine and Protection,2009,29(1):84-87
Telephone information-memory-concentration test used in evaluating cognitive function of patients with nasopharyngeal carcinoma after radiotherapy
Received:May 09, 2008  
DOI:10.3760/cma.j.issn.0254-5098.2009.01.027
KeyWords:Nasopharyngeal neoplasm  Cognitive function  Information-memory-concentration test
FundProject:广西医疗卫生重点科技项目基金资助(200520)
Author NameAffiliation
QIN Ling Department of Neuro-internal Medicine, Peoples Hospital of Guangxi Chuang Autonomous Region, Nanning 530021, China 
YANG Xiao-ye 南宁市红十字会医院 
LI Ling 广西医科大学附属肿瘤医院放 疗科 
邓卓霞 广西壮族自治区人民医院鼻咽癌研究所 
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Abstract::
      Objective To investigate the telephone information-memory-concentration test (TIMCT) in evaluating the cognitive function of patients with nasopharyngeal carcinoma(NPC)after radiotherapy. Methods The cognitive function were evaluated by TIMCT and mini mental state examination (MMSE) in 2 weeks for 30 normal persons and 90 NPC patients. And the 90 NPC patients were divided into the 3 months, 2 years and 5 years after radiotherapy groups. All patients were carried out firstly face to face interview and telephone interview 1 time after 2 weeks. Results The correlation coefficient of all groups between TIMCT(telephone) and TIMCT (face to face) were bigger (R=0.850) when MMSE wasnt control variable. And the correlation coefficients between TIMCT (telephone) and TIMCT (face to face) were lower (R=0.366) when MMSE was control variable. As for examining time was classification factor, TIMCT (telephone) and TIMCT (face to face) were analyzed by partial correlation analysis. Only normal group was correlated with group of 3 months after radiotherapy and group of 2 years after radiotherapy wasnt correlated with group of 5 years after radiotherapy (R=0.447,0.970,0.200 and 0.062). In addition, the difference plot of TIMCT(telephone) and TIMCT (face to face) indicated that telephone was consistent with face to face interview (MMSE≥28). Both telephone and face to face interview reflected the cognitive function downtrend of research objects.Conclusion TIMCT (telephone), TIMCT(face to face) and MMSE (face to face) can reflect cognitive function downterend of patients with NPC after radiotherapy. But TIMCT(telephone)used in clinical screening cognitive function impairment of patients with NPC after radiotherapy should be improved further.
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