HU Wei,YU Chang-hui,SHAO Ming-hai,et al.A application study of dose constraint template in intensity modulated radiation therapy planning for early stage nasopharyngeal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2009,29(1):61-64
A application study of dose constraint template in intensity modulated radiation therapy planning for early stage nasopharyngeal carcinoma
Received:April 24, 2008  
DOI:10.3760/cma.j.issn.0254-5098.2009.01.019
KeyWords:Nasopharyngeal neoplasm  Radiotherapy  Intensity modulated  Dose constraint  Dose template
FundProject:浙江省科学技术厅重大与高发疾病防治技术项目基金资助(2007C13054)
Author NameAffiliationE-mail
HU Wei Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China huw@tzhospital.com 
YU Chang-hui Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China  
SHAO Ming-hai Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China  
杨海华 Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China  
丁维军 Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China  
杨伟芳 Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China  
单国平 Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China  
吴式琇 温州医学院附属第一医院放疗科  
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Abstract::
      Objective To investigate a feasibility of using dose constraint template (DCT) to increase conformity index (CI) of planning target volume (PTV) and improve intensity modulated radiation therapy (IMRT) planning efficiency for early stage nasopharyngeal carcinoma. Methods Ten patients with pathological diagnosed and treated by IMRT were selected for this study. Target volumes were delineated with Corvus 6.3 of treatment planning system, two dose limiting regions(DLR) around PTV were added by extending from PTV,each DLR was 1 cm thick. We created three plans:Plan0,Plan1 and Plan2. Plan0 was without DLR and DCT, Plan1 without DLR but with DCT, Plan2 with both condition; but to compare dose distribution in PLTV and normal tissue using three plans. Results Three plans could fill equal request of dose distribution in PLTV and normal tissue, and their difference was not statistical significant. CI of Plan2 was increased and planning time was decreased significantly compared with Plan0 and Plan1. Conclusion Usage of DCT together with DLR can increase CI of PTV and improve IMRT planning efficiency for early stage nasopharyngeal carcinoma, planning time is shortened significantly.
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