| HU Wei,YU Chang-hui,SHAO Ming-hai.A application study of dose constraint template in intensity modulated radiation therapy planning for early stage nasopharyngeal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2009,29(1):61-64 |
| A application study of dose constraint template in intensity modulated radiation therapy planning for early stage nasopharyngeal carcinoma |
| Received:April 24, 2008 |
| DOI：10.3760/cma.j.issn.0254-5098.2009.01.019 |
| KeyWords:Nasopharyngeal neoplasm Radiotherapy Intensity modulated Dose constraint Dose template |
| FundProject:浙江省科学技术厅重大与高发疾病防治技术项目基金资助(2007C13054) |
| Author Name | Affiliation | E-mail | | HU Wei | Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China | huw@tzhospital.com | | YU Chang-hui | Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China | | | SHAO Ming-hai | Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China | | | 杨海华 | Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China | | | 丁维军 | Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China | | | 杨伟芳 | Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China | | | 单国平 | Department of Radiation Oncology, Zhejiang Taizhou Hospital, Linhai 317000, China | | | 吴式琇 | 温州医学院附属第一医院放疗科 | |
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| Abstract:: |
| Objective To investigate a feasibility of using dose constraint template (DCT) to increase conformity index (CI) of planning target volume (PTV) and improve intensity modulated radiation therapy (IMRT) planning efficiency for early stage nasopharyngeal carcinoma. Methods Ten patients with pathological diagnosed and treated by IMRT were selected for this study. Target volumes were delineated with Corvus 6.3 of treatment planning system, two dose limiting regions(DLR) around PTV were added by extending from PTV,each DLR was 1 cm thick. We created three plans:Plan0,Plan1 and Plan2. Plan0 was without DLR and DCT, Plan1 without DLR but with DCT, Plan2 with both condition; but to compare dose distribution in PLTV and normal tissue using three plans. Results Three plans could fill equal request of dose distribution in PLTV and normal tissue, and their difference was not statistical significant. CI of Plan2 was increased and planning time was decreased significantly compared with Plan0 and Plan1. Conclusion Usage of DCT together with DLR can increase CI of PTV and improve IMRT planning efficiency for early stage nasopharyngeal carcinoma, planning time is shortened significantly. |
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