| HONG Mei,JIANG Zao,NIE Yan,et al.Influence of hyperthermo-radiotherapy on T helper subgroup for patients with esophageal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2009,29(1):39-40 |
| Influence of hyperthermo-radiotherapy on T helper subgroup for patients with esophageal carcinoma |
| Received:May 28, 2008 |
| DOI：10.3760/cma.j.issn.0254-5098.2009.01.011 |
| KeyWords:Esophageal carcinoma Hyperthermia Radiotherapy T helper subgroup |
| FundProject:南京市卫生局医学科技发展基金项目(Ykk05114) |
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| Abstract:: |
| Objective To evaluate the influence of hyperthermia on T helper subgroup (T help type1/T help type2,Th1/Th2) for patients with esophageal carcinoma.Methods 22 patients of esophageal carcinoma were randomly divided into two groups. Both group patients were treated by external radiation, the total dose was 64-66 Gy/30-33 fractions. Radiotherapy was the only therapy method in group A. Hyperthermia was used twice every week, with 8-10 fractions except for radiotherapy in group B. All patients were phlebotomized at the beginning and the end of radiotherapy for examining Th1/Th2 by flow cytometry.Results Th1 was significantly decreased in group A(t=5.33,P<0.01). All indexes in group B had no difference (t=-1.41, P>0.05). The Th1 in group A was decreased much more than that in group B(t=4.28,P<0.05).Conclusion Hyperthermia could rectify the balance of Th1/Th2. |
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