| REN Shi-cheng,LUO Qiong,YANG Ming-liang.Effect of laminaria japonica polysaccharides (LJP) on radiation damage of testis tissue in male rats[J].Chinese Journal of Radiological Medicine and Protection,2007,27(6):540-542 |
| Effect of laminaria japonica polysaccharides (LJP) on radiation damage of testis tissue in male rats |
| Received:November 27, 2006 |
| DOI： |
| KeyWords:Laminaria japonica polysaccharides (LJP) Radiation Testis tissue damage a:正常对照组 b:阴性对照组 c: LJP组 d:阳性对照组 图1 海带多糖对大鼠睾丸组织形态的影响 ×200 |
| FundProject:湖北省科技厅重点攻关项目(2001AA307B) |
| Author Name | Affiliation | E-mail | | REN Shi-cheng | Department of Nutrition and Food Hygiene, School of the Public Health, Wuhan University, Wuhan 430071, China | | | LUO Qiong | Department of Nutrition and Food Hygiene, School of the Public Health, Wuhan University, Wuhan 430071, China | drluoqiong@sina.com | | YANG Ming-liang | Department of Nutrition and Food Hygiene, School of the Public Health, Wuhan University, Wuhan 430071, China | | | 杨佳娟 | Department of Nutrition and Food Hygiene, School of the Public Health, Wuhan University, Wuhan 430071, China | | | 闫俊 | Department of Nutrition and Food Hygiene, School of the Public Health, Wuhan University, Wuhan 430071, China | | | 李卓能 | Department of Nutrition and Food Hygiene, School of the Public Health, Wuhan University, Wuhan 430071, China | | | 王丽红 | Department of Nutrition and Food Hygiene, School of the Public Health, Wuhan University, Wuhan 430071, China | | | 崔晓燕 | Department of Nutrition and Food Hygiene, School of the Public Health, Wuhan University, Wuhan 430071, China | |
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| Abstract:: |
| Objective To observe the effect of laminaria japonica polysaccharides (LJP) on local radiation damage of testis tissue in male rats.Methods The Wistar rats were randomly divided into 4 groups: the normal group, the model group, positive control group and LJP treatment group (50 mg·kg－1·d－1). LJP was applied to the treatment group for 10 d before local irradiation withγ-ray (6.0 Gy). The morphological change of the testis, organ index of testis and epididymides, sperm count, motility rate, superoxide dismutase (SOD) activity and malonic aldehyde (MDA) contents were measured.Results LJP could make the damaged testis recover to near normal, elevate the organ index of testis and epididymides, promote the sperm count and motility rate, increase the activity of SOD and decrease the contents of MDA in testis tissue.Conclusions LJP could inhibit testis tissue damage induced by local radiation, hence enhance the significant radioprotective effect to testis tissue. LJP has the conspicuous protective effect on radiation damage of testis tissue. |
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