HE Yu-xiang,CAI Yong,ZOU Yue,ZHU Xiang-gao.Analysis of influence factors on the volume of pelvic bowel irradiated for rectal cancer[J].Chinese Journal of Radiological Medicine and Protection,2007,27(5):482-485
Analysis of influence factors on the volume of pelvic bowel irradiated for rectal cancer
Received:September 29, 2006  
DOI:
KeyWords:Rectal cancer  Bowel  Bladder  Radiotherapy
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Author NameAffiliationE-mail
HE Yu-xiang Department of Radiation Oncology, Peking University the School Oncology, Beijing 100036, China  
CAI Yong Department of Radiation Oncology, Peking University the School Oncology, Beijing 100036, China caiyong109@sohu.com 
ZOU Yue 第二炮兵总医院  
ZHU Xiang-gao Department of Radiation Oncology, Peking University the School Oncology, Beijing 100036, China  
郭梅 The Affiliated Hospital, Academy of Military Medical Sciences, Beijing100071, China  
韩树奎 Department of Radiation Oncology, Peking University the School Oncology, Beijing 100036, China  
徐博 Department of Radiation Oncology, Peking University the School Oncology, Beijing 100036, China  
王丹红 The Affiliated Hospital, Academy of Military Medical Sciences, Beijing100071, China  
赵红霞 第二炮兵总医院  
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Abstract::
      Objective To evaluate influence of prone supine position, gender, operation, bladder distension on bowel irradiated for patients with rectal cancer during pelvic radiotherapy. Methods 36 patients with rectal cancer were investigated. Treatment plans were created with three dimensional treatment planning system. The dose and volume of bowel irradiated were analyzed according to dose-volume histograms (DVH) for every patient. The prescribed dose was 50 Gy. Results The extent of bladder distension significantly influenced the mean doses and the V45 high dose volumes of bowel irradiated. The treatment position and gender significantly influenced the V15 low dose volume of bowel irradiated, the operation significantly influenced the mean doses of bowel. Either prone and supine position, or preoperative and postoperative, the doses of bowel irradiated for good bladder distension were lower and the volumes were smaller than that for bad bladder distension. The V45 high dose volume of bowel irradiated for bad and good bladder distension at prone position were 15.3% and 7.4%(P=0.023),respectively, and at postoperative 14.1% and 7.2%(P=0.014), respectively. Conclusions The doses and volumes of pelvic bowel irradiated were significantly influenced by the extent of bladder distension, and partly influenced by the prone/supine position, gender and operation.
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