ZHOU Ling-hong,WANG Zhuo-yu,CHEN Chao-min,et al.Study on beam weight optimization with SCG algorithm in intensity modulated radiationtherapy[J].Chinese Journal of Radiological Medicine and Protection,2007,27(3):278-281
Study on beam weight optimization with SCG algorithm in intensity modulated radiationtherapy
Received:May 30, 2006  
DOI:
KeyWords:IMRT  Dose calculation  SCG algorithm  Optimization of beam parameters
FundProject:广东省科技计划资助项目(2005B30301017)
Author NameAffiliation
ZHOU Ling-hong School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China 
WANG Zhuo-yu School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China 
CHEN Chao-min School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China 
唐木涛 济南军区疾病预防控制中心 
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Abstract::
      Objective To study beam weight optimization with Scaled Conjugate Gradient (SCG) algorithm implemented as the intensity modulated radiation therapy(IMRT).Methods The objective function is based on dose constrain as well as the dose homogeneous constrain and important factors of tissue. Two and three dimensional isodose contours and dose-volume histogram are used to evaluate the treatment planning. Results It is shown that beam weight optimization in IMRT based on SCG algorithm can obtain highly conformal dose distributions within a clinically acceptable computation time. SCG algorithm is valid and efficient to accelerate the optimization process. Conclusions SCG may have a wide application in facilitation of IMRT treatment planning.
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