| LÜ Hui-min,JIA Ke-jun,ZHENG Hui,et al.Effect of thorium and rare earth mixed dust on cytokines and haematological indexes of occupational personnel[J].Chinese Journal of Radiological Medicine and Protection,2007,27(3):260-262 |
| Effect of thorium and rare earth mixed dust on cytokines and haematological indexes of occupational personnel |
| Received:November 16, 2006 |
| DOI： |
| KeyWords:Mine dust exposure Immunological function Cytokines Hematology |
| FundProject:科技部科研院所社会公益研究专项项目(2005DIB1J087),公共卫生专项经费(54006-0104) |
| Author Name | Affiliation | E-mail | | LÜ Hui-min | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | | | JIA Ke-jun | 包钢劳动卫生职业病防治研究所 | | | ZHENG Hui | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | | | 涂序珉 | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | | | 刘玉飞 | 包钢劳动卫生职业病防治研究所 | | | 甄荣 | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | | | 张伟 | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | | | 张翠兰 | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | | | 王春燕 | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | | | 郝述霞 | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | | | 苏旭 | National Institute for Radiologcal Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China | suxu@nirp.cn |
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| Abstract:: |
| Objective To study the effects of thorium and rare earth mixed dust on cytokines and haematological indexes of occupational personnel exposed to low dose radiation.Methods Serum IL-2, IL-6 and TNF were analysed by radioimmunoassay and haemocytological indexes were estimated by automatic blood corpuscle analysator.Results Serum IL-2 were (2.267±1.032) pg/ml and (4.608±1.411) pg/ml for exposure and non-exposure groups respectively; IL-6 were (66.55±27.22) pg/ml and (124.3±56.32) pg/ml respectively, showing that levels of IL-2 and IL-6 for exposure groups were lower than that of normal values and decreased than non-exposure groups. Activities of TNF were (0.96±0.33) ng/ml and (0.84±0.35) ng/ml, respectively.It was shown that TNF level of exposure group was obviously higher than that of non-exposure group, although no significant difference was found between two groups for normal reference values. Examination of 14 haematological indexes, among them, 5 indexes of exposure group showed significantly difference compared with those of non-exposure group. Conclusion Thorium and rare earth mixed dust might affect some immunological function and haematological indexes of occupational personnels chronically exposed to low dose radiation. |
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