| LI Jian-cheng,YU Xin-sheng,JIANG Guo-liang.Dosimetry of parotid glands in IMRT plan of nasopharyngeal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2007,27(3):248-250 |
| Dosimetry of parotid glands in IMRT plan of nasopharyngeal carcinoma |
| Received:June 16, 2006 |
| DOI： |
| KeyWords:Intensity-modulated radiation therapy Nasopharyngeal carcinoma Parotid |
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| Abstract:: |
| Objective To evaluate the effect of different intensity-modulated radiation therapy (IMRT) plan on the dosimetry of parotid in patients with nasopharyngeal carcinoma.Methods Under the same constraints and objections, the IMRT plan of nasopharyngeal carcinoma with sparing unilateral parotid and the IMRT plan added plan tumor volume (PTV) margin for parotid gland was investigated.Results Between conventional IMRT plan and the IMRT plan spared unilateral parotid, their target coverage, homogeneity index and conformal index of PTV70 is similar. On PTV60, Dmin in the plan of sparing one parotid gland was more than that in normal IMRT plan (P<0.01), D95 in the plan of sparing one parotid gland have improved (P<0.01), Compared with normal IMRT plan, D50%VOL and Dmean of parotid gland were similar between the two plans. Between conventional IMRT plan and the IMRT plan added 2 or 3 mm margin for parotid gland, their target coverage, homogeneity index and conformal index of PTV70 is similar. Dmin, Dmean and D95 of PTV60 have decreased tendency from normal IMRT plan to 2mm margin plan to3mm margin plan. Dmax of brainstem and spine cord have increased tendency from normal IMRT plan to 2mm margin plan to 3mm margin plan. Conclusions The IMRT plan of nasopharyngeal carcinoma with sparing unilateral parotid may be adopted not to protect both two parotids, while PTV margin for parotid added as parotid move. |
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