WU Ai-qin,ZHENG Wen-long,XU Chong-yong,et al.The application and shielding value of low-dose CT scanning in hypoxic ischemic encephalopathy of neonate[J].Chinese Journal of Radiological Medicine and Protection,2006,26(5):528-530
The application and shielding value of low-dose CT scanning in hypoxic ischemic encephalopathy of neonate
Received:January 08, 2006  
DOI:
KeyWords:Radiation dose  Tomography  Brain  Newborn
FundProject:温州市科技局基金资助项目(Y2004A067)
Author NameAffiliation
WU Ai-qin Department of Radiology, Yuying Children's Hospital of Wenzhou Medical College, Wenzhou 325000, China 
ZHENG Wen-long 温州市第二人民医院放射科 
XU Chong-yong Department of Radiology, Yuying Children's Hospital of Wenzhou Medical College, Wenzhou 325000, China 
程建敏 Department of Radiology, Yuying Children's Hospital of Wenzhou Medical College, Wenzhou 325000, China 
陈宇 Department of Radiology, Yuying Children's Hospital of Wenzhou Medical College, Wenzhou 325000, China 
陈廷港 Department of Radiology, Yuying Children's Hospital of Wenzhou Medical College, Wenzhou 325000, China 
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Abstract::
      Objective To investigate the application and shielding value of multi-slice spiral CT scanning with low-dose in hypoxic ischemic encephalopathy (HIE) of neonate. Methods 60 neonates with HIE diagnosed by clinic were prospectively selected and randomly divided into two groups averagely. The technical parameters were tube tension 120 kV, slice thickness and gap 6 mm, conventional tube current 250 mAs and low dose 50 mAs. Weighted CT dose index (CTDIw) and dose length product (DLP) were compared to each other. The image noise were analyzed with water phantom of children's skull. The mean and standard deviation of CT value were statistically analyzed. The image quality was blindly evaluated in two different dose groups. Results (1) The mAs, CTDIw and DLP in low dose group were 20% of conventional dose group; (2) The noise of water phantom in low dose group was larger than in conventional dose group with the significant difference (t=34.533, P<0.01); (3) The imaging quality in low dose group was mostly better,but inferior to conventional dose group, while there is no poor images to influence the diagnosis of HIE. Conclusions The low dose scanning will be practical in diagnosis of HIE, and beneficial to protect the newborn which corresponds to the optimizing principle of ICRP in medical radiation protection.
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