| FANG Tong,FENG Guo-sheng,Liu Li,et al.Pilot study on combined three-dimensional conformal radotherapy and transcatheter arterial chemoembolization for portal vein tumor thrombus in patients with unresectable hepatocellular carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2006,26(5):476-478 |
| Pilot study on combined three-dimensional conformal radotherapy and transcatheter arterial chemoembolization for portal vein tumor thrombus in patients with unresectable hepatocellular carcinoma |
| Received:May 22, 2006 |
| DOI： |
| KeyWords:Hepatocellular carcinoma Portal thrombus Radiotherapy Transcatheter arterial chemoembolization |
| FundProject: |
| Author Name | Affiliation | | FANG Tong | Departement of Radiation Oncology, Beijing Shijitan Hospital. Beijing 100038, China | | FENG Guo-sheng | Departement of Radiation Oncology, Beijing Shijitan Hospital. Beijing 100038, China | | Liu Li | 内蒙古医学院附属人民医院 | | 孙保锦 | Departement of Radiation Oncology, Beijing Shijitan Hospital. Beijing 100038, China | | 陈力 | Departement of Radiation Oncology, Beijing Shijitan Hospital. Beijing 100038, China | | 高宏 | Departement of Radiation Oncology, Beijing Shijitan Hospital. Beijing 100038, China |
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| Abstract:: |
| Objective To study clinical therapeutic effctiveness of combined 3-dimensional conformal radiotherapy(3DCRT)and transcatheter arterial chemoembolization for portal vein tumor thrombus(PVTT)in unresectable hepatocellular carcinoma(HCC). Methods 33 patients with unresectable hepatocellular carcinoma complicated with tumor thrombus in the portal vein were enroled in this study. RT was started 1-2 fractions following TACE. A total dose of 45-60 Gy was given as daily 2-4 Gy fractions, with the gross tumor volume(GTV) defined as only PVTT, 90% isodose line covering PTV. Results The effective rate was 54.6%. Survival rates at year 1 and 2 were 45.5% and 21.2%, respectively. Conclusions 3DCRT combined with TACE is an effective method in the treatment of portal vein tumor thrombus in unresectable hepatocellular carcinoma. |
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