| CHEN Chao-min,TANG Mu-tao,ZHOU Ling-hong,et al.Study of dose calculation and beam parameters optimization with genetic algorithm in IMRT[J].Chinese Journal of Radiological Medicine and Protection,2006,26(3):248-250 |
| Study of dose calculation and beam parameters optimization with genetic algorithm in IMRT |
| Received:July 11, 2005 |
| DOI： |
| KeyWords:IMRT Dose calculation Convolution Genetic algorithm Parameters optimization |
| FundProject:广东省科技计划资助项目(2003C32724);广州市科技攻关资助项目(2003Z3-E0411) |
| Author Name | Affiliation | E-mail | | CHEN Chao-min | School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China | gzccm@fimmu.com | | TANG Mu-tao | School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China | | | ZHOU Ling-hong | School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China | | | 吕庆文 | School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China | | | 王卓宇 | School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China | | | 陈光杰 | School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China | |
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| Abstract:: |
| Objective To study the construction of dose calculation model and the method of automatic beam parameters selection in IMRT. Methods The three-dimension convolution dose calculation model of photon was constructed with the methods of Fast Fourier Transform. The objective function based on dose constrain was used to evaluate the fitness of individuals. The beam weights were optimized with genetic algorithm. Results After 100 iterative analyses, the treatment planning system produced highly conformal and homogeneous dose distributions. Conclusion the three-dimension convolution dose calculation model of photon gave more accurate results than the conventional models; genetic algorithm is valid and efficient in IMRT beam parameters optimization. |
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