FENG Chong-jin,RAN Wei,LI Chu-yu.Clinical characteristics and treatment of radioactive osteomyelitis of jaws[J].Chinese Journal of Radiological Medicine and Protection,2006,26(2):159-160
Clinical characteristics and treatment of radioactive osteomyelitis of jaws
Received:September 27, 2005  
DOI:
KeyWords:Jaws  Radioactive osteomyelitis of jaws  Treatment
FundProject:广东省科技计划基金资助项目(2004B30901012)
Author NameAffiliation
FENG Chong-jin Department of Stomatology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China 
RAN Wei Department of Stomatology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China 
LI Chu-yu 中山大学附属肿瘤医院放疗科 
郭俊兵 Department of Stomatology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China 
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Abstract::
      Objective To investigate the clinical characteristics and treatment of radiation osteomyelitis of jaws(ROJ). Methods The clinical records of 65 ROJ cases treated during the period from 1991 through 2003 were examined. Results The average dose of radiotherapy was 70.2 Gy. ROJ were more common in the mandible (72%) and in the first four years after radiotherapy (86%). Conservative treatment relieved the symptoms and controlled the progress of the diseases. The cure rate of ROJ was 92% by extensive resection of sequestrum. The survival rate of transplant flap was 95% with immediate vascularized tissue graft. Conclusion 70 Gy can be regarded as reference threshold for clinical irradiation. Extensive resection of sequestrum in combination with immediate vascularized tissue grafts clearly improved the prognosis of radiation osteomyelitis of jaws.
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