| CHEN Ying,LIU Xiu-lin,ZHANG Xue-qing.Biological dose estimation and late effect evaluation of the exposed persons in Harbin radiation accident[J].Chinese Journal of Radiological Medicine and Protection,2006,26(2):125-128 |
| Biological dose estimation and late effect evaluation of the exposed persons in Harbin radiation accident |
| Received:January 08, 2006 |
| DOI： |
| KeyWords:Protracted irradiation Dic+r Stable aberrations Biological dose Late effect |
| FundProject: |
| Author Name | Affiliation | E-mail | | CHEN Ying | Beijing Institute of Radiation Medicine, Beijing, 100850, China | yingchen29@ywhoo.com.cn | | LIU Xiu-lin | Beijing Institute of Radiation Medicine, Beijing, 100850, China | | | ZHANG Xue-qing | Beijing Institute of Radiation Medicine, Beijing, 100850, China | | | 骆亿生 | Beijing Institute of Radiation Medicine, Beijing, 100850, China | |
|
| Hits: 3212 |
| Download times: 2008 |
| Abstract:: |
| Objective To estimate cumulative exposure doses and evaluate late effects for 2 heavilly exposed persons of Harbin 192Ir protracted irradiated accident in 2005. Methods Conventional chromosome, Cyt-B micronucleus and G-banding specimens were prepared and the biological doses of 2 victims were estimated with dose-response curves of dicentrics+rings and micronuclei. Stable chromosome aberrations were analyzed by AMMS-I karyotype auto-analysis system for dose reconstruction. Results The frequencies of dic+r and MN in the victim H were 23.5% and 320‰ respectively, in J victim 6.6% and 81‰ respectively. Bio-doses of the victim H and J are equivalent to 1.6-2.2Gy and 0.7-0.8 Gy single uniform whole body exposure. The results of G-band karyotype analysis indicate stable aberration frequency was 40% for victim H with some complicated aberrations, and 6% for victim J. Cumulative exposure doses estimated by stable aberrations were a little higher than dic+r. Conclusion Two victims were exposed to relatively uniform whole body irradiation. The cumulative doses of victims H and J have reached medium or slight degree ARS levels, respectively. They should be followed up closely. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
