| ZHANG Shu-lan,KE Xiao-yan,JIA Ting-zhen.Anti-infection treatment of iatrogenic acute radiation sickness[J].Chinese Journal of Radiological Medicine and Protection,2006,26(1):20-22 |
| Anti-infection treatment of iatrogenic acute radiation sickness |
| Received:September 28, 2005 |
| DOI： |
| KeyWords:Iatrogenic acute radiation sickness Hemopoietic stem cell TBI Anti-infection |
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| Abstract:: |
| Objective To occumulatle experience of anti-infection treatment in acute radiation sickness（ARS）induced by medical treatment in order to provide beneficial help for victims of accidental of acute radiation sickness. Methods The changes of peripheral blood indices,body temperature and clinical symptoms of 17 cases who were clinically irradiated with 6.0-7.2 Gy X-rays were observed both before peripheral blood stem cell transplantation（PBSCT） and after anti-infection treatment. Results WBC count began to decrease to below 1×109/L from the 8th to 10th days after irradiation and maintained at low level for 4 days or for 13.3 days if the patients had not received rhG-CSF treatment.In 29.4% of patients the body temperature was higher than 38.5℃.After comprehensive enviromental protection and anti-infection treatment,all patients could successfully tide over the period of bone marrow depression without appearance of the typical critical phase of ARS. Conclusion PBSCT and rhG-CSF treatment can reduce the time span for reconstruction of bone marrow.Comprehensive enviromental protection and combined anti-infection treatment are key points for successful treatment. |
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