| LIU Chang-an,SUN Quan-fu,LI Xiao-juan.Relationship between the time of vomiting onset and whole-body dose in victims accidentally exposed to gamma-rays[J].Chinese Journal of Radiological Medicine and Protection,2005,25(5):409-411 |
| Relationship between the time of vomiting onset and whole-body dose in victims accidentally exposed to gamma-rays |
| Received:April 16, 2005 |
| DOI： |
| KeyWords:Radiation accident Gamma-ray Vomiting Absorbed dose Triage of injured persons |
| FundProject:科技部科研院所社会公益研究专项国家科技基础条件工作重点项目(2003DIA6N009) |
| Author Name | Affiliation | | LIU Chang-an | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | SUN Quan-fu | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | LI Xiao-juan | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | 陈尔东 | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | 刘英 | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China |
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| Abstract:: |
| Objective To explore the mathematical relationship between the time of vomiting onset and whole-body dose in victims accidentally exposed to gamma-rays. Methods The data of 39 historical cases accidentally exposed to gamma-rays were analyzed and tested with STATA statistical software package. Results The frequency of vomiting occurrence in cases with whole-body dose of 1 Gy or more (22/27) was significantly higher than those of within 1 Gy(1/12) (P<0.001). For patients who experienced vomiting, the time of vomiting onset post-irradiation (TD, in hour) decreased with increase of the whole-body absorbed dose (D, in Gy) according to a power function model, which could be described by the formula: TD =(17.45±1.77)D-(2.21±0.30)(n=23,F=50.01,P<0.01,adjusted R2=0.8099 ). The P25, P50 and P75 doses for patients appearing vomiting less than 2 hours post-exposure were 4.1 Gy, 7.6 Gy and 11.0 Gy, respectively, and those for the time of vomiting onset more than 2 hours were 2 Gy, 2.4 Gy and 2.59 Gy, respectively. Conclusion From these data, the time of vomiting onset would appear to be a rapid and useful early triage index in radiological emergency circumstances where a large number of patients are anticipated, however, the limitations of which should be taken into consideration. |
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