| WEI Yan,YAN Chen-hua,SHI Hui-lin.Role of cytochemical staining in diagnosis of monocytic leukemia[J].Chinese Journal of Radiological Medicine and Protection,2005,25(4):354-356 |
| Role of cytochemical staining in diagnosis of monocytic leukemia |
| Received:April 24, 2005 |
| DOI： |
| KeyWords:Acute monocytic leukemia Acute myelomonocytic leukemia Morphology Immunophenotype Diagnosis Cytogenetics |
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| Author Name | Affiliation | | WEI Yan | Institute of Hematology, The People's Hospital, Peking University, Beijing 100044, China | | YAN Chen-hua | Institute of Hematology, The People's Hospital, Peking University, Beijing 100044, China | | SHI Hui-lin | Institute of Hematology, The People's Hospital, Peking University, Beijing 100044, China | | 刘艳荣 | Institute of Hematology, The People's Hospital, Peking University, Beijing 100044, China | | 邱镜莹 | Institute of Hematology, The People's Hospital, Peking University, Beijing 100044, China | | 江滨 | Institute of Hematology, The People's Hospital, Peking University, Beijing 100044, China | | 王德炳 | Institute of Hematology, The People's Hospital, Peking University, Beijing 100044, China |
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| Abstract:: |
| Objective To explore the role of cytochemical staining in MIC(morphology,immunology and cytogenetics) typing of acute monocytic leukemia(AML-M5)and acute myelomonocytic leukemia (AML-M4). Methods We analyzed the characteristics of morphology,immunology and cytogenetics in 47 cases of diagnosed AML. Results Eventually,they were diagnosed with MIC.There were 25 cases with AML-M5,19 cases with AML-M4(consisted of 5 cases diagnosed AML-M4Eo),2 cases with acute myeloid leukemia with t(8∶21) and 1 case with T-ALL. Conclusions During MIC typing of AML-M4 and AML-M5, the diagnostic value of morphology remains important, for immunophenotype,cytogenetics and morphology are interdependent. Immunophenotype and cytogenetics are necessary for improvement of the accuracy rate of diagnosis. |
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