XU Hui-qin,LIU Gong-chuan,JIN Ao-xing.Study on effect of DL-BSO on GSH content in rat C6 glioma cells[J].Chinese Journal of Radiological Medicine and Protection,2005,25(1):47-49 |
Study on effect of DL-BSO on GSH content in rat C6 glioma cells |
Received:February 28, 2004 |
DOI: |
KeyWords:DL-buthionine sulfoximine Rat C6 glioma cells Glutathione |
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Abstract:: |
Objective To observe the effect of DL-buthionine sulfoximine (DL-BSO) on GSH content in rat C6 glioma cells. Method Tietze method was used to detect the effect of DL-BSO on GSH content. Results The GSH content in rat C6 glioma cells reduced effectively after DL-BSO treatment, the reduction speed showed down with time,and the lowest value of the GSH content was 6.08% of that of the control. Conclusion DL-BSO can deplete intracellular GSH content in rat C6 glioma cells. |
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