XU Hui-qin,LIU Gong-chuan,JIN Ao-xing.Study on effect of DL-BSO on GSH content in rat C6 glioma cells[J].Chinese Journal of Radiological Medicine and Protection,2005,25(1):47-49
Study on effect of DL-BSO on GSH content in rat C6 glioma cells
Received:February 28, 2004  
DOI:
KeyWords:DL-buthionine sulfoximine  Rat C6 glioma cells  Glutathione
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Author NameAffiliation
XU Hui-qin Department of Nuclear Medicine, First Affiliated Hospital of Anhui Medical University, Hefei 230022, China 
LIU Gong-chuan 30022 合肥, 安徽医科大学第一附属医院核医学科 
JIN Ao-xing 30022 合肥, 安徽医科大学核医学教研室 
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Abstract::
      Objective To observe the effect of DL-buthionine sulfoximine (DL-BSO) on GSH content in rat C6 glioma cells. Method Tietze method was used to detect the effect of DL-BSO on GSH content. Results The GSH content in rat C6 glioma cells reduced effectively after DL-BSO treatment, the reduction speed showed down with time,and the lowest value of the GSH content was 6.08% of that of the control. Conclusion DL-BSO can deplete intracellular GSH content in rat C6 glioma cells.
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