| LIU Wei,LIN Hai-qun,LI Xin-luan,et al.Application of FISH in dose reconstruction for workers exposed to radiations in oil field and chemical industry[J].Chinese Journal of Radiological Medicine and Protection,2005,25(1):34-36 |
| Application of FISH in dose reconstruction for workers exposed to radiations in oil field and chemical industry |
| Received:May 08, 2004 |
| DOI： |
| KeyWords:FISH Translocation Dose reconstruction Chromosome aberration |
| FundProject:中国石化集团公司基金资助项目(J302010) |
| Author Name | Affiliation | | LIU Wei | Institute of Radiation Medicine, Shandong Academy of Medical Sciences, Jinan 250062, China | | LIN Hai-qun | Institute of Radiation Medicine, Shandong Academy of Medical Sciences, Jinan 250062, China | | LI Xin-luan | 中国石化集团公司青岛安全工程研究院； | | 高敏 | 中国石化集团公司青岛安全工程研究院； | | 邵华 | 中国石化集团公司青岛安全工程研究院； | | 李洁清 | Institute of Radiation Medicine, Shandong Academy of Medical Sciences, Jinan 250062, China | | 侯殿俊 | Institute of Radiation Medicine, Shandong Academy of Medical Sciences, Jinan 250062, China | | 乔健维 | Institute of Radiation Medicine, Shandong Academy of Medical Sciences, Jinan 250062, China | | 商希梅 | Institute of Radiation Medicine, Shandong Academy of Medical Sciences, Jinan 250062, China |
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| Abstract:: |
| Objective To explore the usage of FISH in retrospective biodosimetry for individuals who had chronically exposed to ionizing radiation. Methods Chromosomal aberrations from 22 occupational workers having exposed to X-ray radiation and from 10 controls were analysed using FISH with probes for chromosomes 1,4. Results The frequencies of translocation and total aberrations observed in X-ray workers were statistically higher than those of controls.The longer working time one had the higher frequency of translocation. Conclusion The results indicate it is possible that FISH can be used in retrospective biodosimetry for individuals who have chronically exposed to ionizing radiation. |
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