| YUAN Shu-yu,DAI Guang-fu,LIU Yin,et al.Study of dose-influencing factors in endovascular brachytherapy[J].Chinese Journal of Radiological Medicine and Protection,2004,24(4):364-366 |
| Study of dose-influencing factors in endovascular brachytherapy |
| Received:December 18, 2003 |
| DOI： |
| KeyWords:Brachytherapy Thermoluminescence dosimetry Absorbed dose Tissue equivalent blood vessel |
| FundProject:国家自然科学基金资助项目(30170233) |
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| Abstract:: |
| Objective To study the 32 P balloon beta dose-influencing factors in preventing endovascular restenosis. Methods The blood vessel wall was substituted by muscle equivalent material.Determination of the dose of the vessel wall was performed by thermoluminescence dosimetric method. Results When 32 P liquid remained in the empty balloon, the dose of the vessel wall was increased by 0.92 Gy/min. When the center catheter was closed to the balloon wall, the absorbed dose of the balloon surface decreased by 20%. When there were air bubbles in the balloon, the dose adjacent to air bubble lowered by 30% than the average absorbed dose of balloon surface. Conclusions The results show that the axisal absorbed dose of 32 P on balloon surface is uniform but the radial dose distribution is attenuated very rapidly with distance. The endovascular brachytherapy has good perspectives, but there are many problems to be solved for its clinical application. |
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