| LI Li-jun,GAO Hong,FENG Guo-sheng,et al.Radiochemotherapy with interstitial implantation of 125I seeds and 5-FU slow-release seeds for recurrent thyroid cancer[J].Chinese Journal of Radiological Medicine and Protection,2004,24(4):346-347 |
| Radiochemotherapy with interstitial implantation of 125I seeds and 5-FU slow-release seeds for recurrent thyroid cancer |
| Received:March 10, 2004 |
| DOI： |
| KeyWords:Thyroid cancer 125I seeds 5-FU slow-release seeds Brachytherapy |
| FundProject: |
| Author Name | Affiliation | | LI Li-jun | Tumor Center, Beijing Railway General Hospital, Beijing 100038, China | | GAO Hong | Tumor Center, Beijing Railway General Hospital, Beijing 100038, China | | FENG Guo-sheng | Tumor Center, Beijing Railway General Hospital, Beijing 100038, China | | 刘璐 | Tumor Center, Beijing Railway General Hospital, Beijing 100038, China | | 周桂霞 | | | 王慧宇 | Tumor Center, Beijing Railway General Hospital, Beijing 100038, China | | 胡晓东 | | | 朱晓兰 | Tumor Center, Beijing Railway General Hospital, Beijing 100038, China | | 杜伟生 | Tumor Center, Beijing Railway General Hospital, Beijing 100038, China |
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| Abstract:: |
| Objective To investigate the combined treatment technological feasibility, efficacy with interstitial implantation of 125 I seeds and 5-FU slow-release seeds for recurrent thyroid cancer. Methods From March 2002 to December 2003, 9 cases of recurrent thyroid cancer were treated with radiochemotherapy. They were all patients with recurrent thyroid cancer after operation and radiation. We implanted alternately 125 I seeds and 5-FU slow-release seeds by guiding of treatment planning system. The MPD of 125 I seed implantation were 60-90 Gy. The mean 8 granules of 125I seeds and 5-FU 200 mg were used in every patient. Results Fully operating procedure was accomplished for all the patients. No operating complication occurred.No displacement of 125 I seeds was found by cervical X-ray. CT scan showed that the reduced size of tumor changed in different degree. The CR was 11.11%(1/9). The PR was 66.66%(6/9). The NC was 22.22% (2/9). Following up 8-26 months, all patients survived. Conclusion Using radiochemotherapy with interstitial implantation of 125I seeds and 5-Fu slow-release seeds is safe, minimally invasive and effective for treatment of recurrent thyroid cancer. |
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