ZHENG Hui,ZHEN Rong,NIU Hui-sheng,et al.Radioisotope 45Ca labeling four calcium chemical compounds and tracing calcium bioavailability[J].Chinese Journal of Radiological Medicine and Protection,2004,24(4):336-338
Radioisotope 45Ca labeling four calcium chemical compounds and tracing calcium bioavailability
Received:April 24, 2004  
DOI:
KeyWords:Radioisotope 45Ca  Radiolabeling  Bioavailability  Calcium gluconate  Calcium citrinate  Calcium carbonate  Calcium L-threonate
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Author NameAffiliation
ZHENG Hui National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China 
ZHEN Rong National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China 
NIU Hui-sheng  
李怀芬  
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Abstract::
      Objective To build up a new method of the radioisotope 45 Ca labeling four calcium chemical compounds, observe and tracing bioavailability change of calcium labeled with radioisotope 45 Ca. Methods The calcium gluconate(Ca-Glu), calcium citrinate(Ca-Cit), calcium carbonatte(Ca-Car) and calcium L-threonate(Ca-Thr)were labeled by radioisotope 45 Ca. Four calcium chemical compounds of 45 Ca labeling were used of calcium content 200 mg/kg in the rats and measure the absorption content and bioavailability of calcium in tissue of heart, lever spleen, stomach, kidney, brain, intestine, whole blood, urine, faeces. Results ① Radioisotope 45 Ca labeling calcium chemical compound has high radio intensity, more steady standard curve and recover rate. ② The absorption of organic calcium chemical compounds is higher than the inorganic calcium chemical compound in the study of calcium bioavailability. Conclusion The method of tracing with radioisotope45 Ca labeling calcium chemical compounds has the characteristic of the sensitive, objective, accurate and steady in the study of calcium bioavailability.
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