| WANG Dai-you,YU Da-hai,WEN Yu-ming,et al.Establishment of an animal model of mice with radiation-injured soft tissue blood vessels[J].Chinese Journal of Radiological Medicine and Protection,2004,24(4):302-303 |
| Establishment of an animal model of mice with radiation-injured soft tissue blood vessels |
| Received:November 18, 2003 |
| DOI： |
| KeyWords:Vascular endothelial cells Radiation injury Animal model |
| FundProject:国家自然科学基金资助项目(30060083) |
| Author Name | Affiliation | | WANG Dai-you | The Department of Oral Maxillofacial Surgery, Stomatological Hospital, Guangxi Medical University, Nanning 530021, China | | YU Da-hai | The Department of Oral Maxillofacial Surgery, Stomatological Hospital, Guangxi Medical University, Nanning 530021, China | | WEN Yu-ming | | | 巫家晓 | The Department of Oral Maxillofacial Surgery, Stomatological Hospital, Guangxi Medical University, Nanning 530021, China | | 韦山良 | The Department of Oral Maxillofacial Surgery, Stomatological Hospital, Guangxi Medical University, Nanning 530021, China |
|
| Hits: 3301 |
| Download times: 1906 |
| Abstract:: |
| Objective The aim of this study was to establish an animal model of mice with radiation -injured soft tissue blood vessels. Methods Forty male mice were irradiated with 30 Gy on the right leg. After the irradiation was finished each of the 40 male mice was tested with angiography, and its muscle tissues on the bilateral legs were examined with vessel staining assay and electron microscopy. Results The results showed that the number of vessels on the right leg was less than that on the left leg, the microvessel density, average diameter and average sectional aera of the right leg were all lower than those of the left, and the configuration and ultra-structure of vessels were also different between both sides of legs. Conclusion In the study we successfully established an animal model of mice with radiation-injured soft tissue blood vessels. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
