| ZOU Jian-ming,SUN Quan-fu,LIU Yu-sheng,et al.Reanalysis of noncancer deaths(1987-1995) among residents in high background radiation area of Yangjiang, China[J].Chinese Journal of Radiological Medicine and Protection,2004,24(2):149-152 |
| Reanalysis of noncancer deaths(1987-1995) among residents in high background radiation area of Yangjiang, China |
| Received:October 28, 2003 |
| DOI： |
| KeyWords:High-background radiation Noncancer death Relative risk Low dose |
| FundProject:日本体质研究会基金资助 |
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| Abstract:: |
| Objective To further analyze non-cancer mortality rates and relevant influencing factors among the residents in high background radiation area(HBRA)and its control area(CA). Methods The data for the period 1987-1995 were obtained from a fixed cohort by prospective survey. The mortality investigation on the spot consisted of two steps, i. e. the follow-up of the cohort members and the ascertainment of causes of death. On the basis of the hamlet-specific average of annual external dose, the cohort members were classified into four groups for internal comparison:high, medial and low dose groups in HBRA and control group in CA. Relative risk(RR), excess relative risk(ERR/Sv)and its 95% confidence interval(CI) were estimated using AMFIT program in Epicure. Results During the period 1987-1995, the noncancer mortality in HBRA increased by 9% compared with that in the control group, and the relative risk of noncancer diseases was 1. 09(P =0. 01), indicating a statistically significant excess mortality in the HBRA. The significantly increased noncancer death was caused by diseases of digestive system, with a RR of 1. 46(P =0. 006);the relative risk of chronic liver diseases including cirrhosis was 1. 98(P =0. 004). The significantly decreased noncancer death rates were observed for the infectious and parasitic diseases, the RR being 0. 81(P=0. 04);for pulmonary tuberculosis, RR 0. 58(P <0. 001). The homogeneity tests of risks across the four dose-groups revealed that the RRs for diseases of digestive system and for liver cirrhosis were significantly different, P values being 0. 01 and 0. 04, respectively. The ERR(95%CI)/Sv for diseases of digestive system and liver cirrhosis were 2. 18(0. 22, 7. 64)and 10. 94(1. 34, NA), respectively. Conclusion The death rates from diseases of digestive system, especially chronic liver diseases and cirrhosis were statistically significantly higher, and that from pulmonary tuberculosis was significantly lower in the HBRA than those in the control area. It is difficult to attribute those risks to chronic natural radiation exposure because of limitations of our data. |
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