WEI Peng-xiang,AI Quan-shan,CHEN Xu.X knife treatment of epilepsy[J].Chinese Journal of Radiological Medicine and Protection,2004,24(1):57-59 |
X knife treatment of epilepsy |
Received:July 19, 2003 |
DOI: |
KeyWords:Secondary epilepsy Idiopathic temporal lobe epilepsy X knife Treatment |
FundProject:解放军沈阳军区科研课题(1999);吉林省卫生厅科研课题(1998011) |
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Abstract:: |
Objective To investigate the curative effect of X knife treatment method for secondary epilepsy (SEp) and idiopathic temporal lobe epilepsy (ITLEp). Methods The 24-hour EEG,CT,MRI were used for locating the epileptogenic lesion of SEp.Forty patients of SEp were treated to destroy epileptogenic lesion by X knife with dose,20-30 Gy.Thirty patients of ITLEp were treated with X knife for amygdalectomy at 140 Gy and collimator 7-10 mm.The 140 Gy were given either by single full dose or 2-time fractionated treatment (Q.24.h). Results By 4-24 month follow-up of all these patients it was showed that seizures were alleviated completly in 50 patients (SEp 32 cases,ITLEp 18 cases),alleviated over 50% in 20 patients (SEp 8 cases,ITLEp 12 cases).No complications were observed. Conclusion X knife treatment of SEp is a useful and safe method to destroy epileptogenic lesion in patients with SEp and to perform amygdalectomy in patients with ITLEp.This methods is thus proved to be effective for such patients. |
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