WEI Peng-xiang,AI Quan-shan,CHEN Xu.X knife treatment of epilepsy[J].Chinese Journal of Radiological Medicine and Protection,2004,24(1):57-59
X knife treatment of epilepsy
Received:July 19, 2003  
DOI:
KeyWords:Secondary epilepsy  Idiopathic temporal lobe epilepsy  X knife  Treatment
FundProject:解放军沈阳军区科研课题(1999);吉林省卫生厅科研课题(1998011)
Author NameAffiliation
WEI Peng-xiang Neurosurgical Department of Beijing Friendship Hospital, Beijing 100050, China 
AI Quan-shan Neurosurgical Department of Beijing Friendship Hospital, Beijing 100050, China 
CHEN Xu Neurosurgical Department of Beijing Friendship Hospital, Beijing 100050, China 
夏吉勇 Neurosurgical Department of Beijing Friendship Hospital, Beijing 100050, China 
陈炳桓 100050 北京, 北京天坛医院神经外科 
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Abstract::
      Objective To investigate the curative effect of X knife treatment method for secondary epilepsy (SEp) and idiopathic temporal lobe epilepsy (ITLEp). Methods The 24-hour EEG,CT,MRI were used for locating the epileptogenic lesion of SEp.Forty patients of SEp were treated to destroy epileptogenic lesion by X knife with dose,20-30 Gy.Thirty patients of ITLEp were treated with X knife for amygdalectomy at 140 Gy and collimator 7-10 mm.The 140 Gy were given either by single full dose or 2-time fractionated treatment (Q.24.h). Results By 4-24 month follow-up of all these patients it was showed that seizures were alleviated completly in 50 patients (SEp 32 cases,ITLEp 18 cases),alleviated over 50% in 20 patients (SEp 8 cases,ITLEp 12 cases).No complications were observed. Conclusion X knife treatment of SEp is a useful and safe method to destroy epileptogenic lesion in patients with SEp and to perform amygdalectomy in patients with ITLEp.This methods is thus proved to be effective for such patients.
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