LIANG Jun,ZHAO Jian-dong.Effects of carbogen plus low concentration oxygen radiotherapy on murine intestinal epithelium[J].Chinese Journal of Radiological Medicine and Protection,2004,24(1):34-36
Effects of carbogen plus low concentration oxygen radiotherapy on murine intestinal epithelium
Received:July 15, 2003  
DOI:
KeyWords:Carbogen plus low concentration oxygen radiotherapy  Murine intestinal epithelium  Radioprotective effect
FundProject:青岛科学技术委员会基金资助项目(200028)
Author NameAffiliation
LIANG Jun Department of Oncology, The Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, China 
ZHAO Jian-dong Department of Oncology, The Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, China 
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Abstract::
      Objective To investigate the effects of carbogen plus low concentration oxygen radiotherapy on murine intestinal epithelium. Methods Kun Ming mice were divided into four groups:Air,HO,LO and HO+ LO.The abdomen of mice was irradiated with 6 MV X-rays at different single doses.The relationship between total cell survival per circumference and radiation dose was established,and dose-survival curves were fitted.Radioprotective factors(RPFs) were calculated. Results The RPF of groups HO,LO and HO+LO was 0.79,1.25 and 1.06,respectively. Conclusion Inhalation of low concentration oxygen can eradicate the enhanced damage by carbogen and possesses certain radioprotective effect.
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