| LI Erzhou,LI Qing,YAN Maosheng.Clinical research of teeth damage from radiotherapy[J].Chinese Journal of Radiological Medicine and Protection,2003,23(4):287-288 |
| Clinical research of teeth damage from radiotherapy |
| Received:December 25, 2002 |
| DOI： |
| KeyWords:Radiation damage Caries |
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| Abstract:: |
| Objective To analyze various factors inducing teeth damage from radiotherapy and the preventive and treatment methods. Methods One hundred cases of patients treated by radiotherapy were divided into two groups. In group one there were 60 cases whose teeth were irradiated during treatment;in group two there were 40 cases whose teeth were not irradiated during treatment. Results The caries incidence was 60% for group one and 15% for group two(PP<0.01).By auto-control in 15 patients, the caries incidence on the sick side was obviously higher than that of the healthy side. Hundred percent caries incidence was found in 6 cases who received a dosage of 70 Gy. Conclusion The authors believe that radiation damage to the teeth is associated with the following factors:1. The dosage and location of irradiation are closely related to caries incidence;2.The active dentinoblasts are very sensitive to radiation;3.Damage to the salivary glands from radiotherapy can result in reduction of salvia and pH value, leading to a high growth rate of Streptococcus mutans. Following preventive measures could be considered in future cases: to apply a caries prevention coating or protective dental crown and TPS, to adjust the dose and time of irradiation, to select conformal radiotherapy technique. The key points for protecting the teeth and salivary gland from caries and damage are protection of the proliferation ability of pulp cells, anti-inflammation, promotion of microcirculation, and strengthening body resistance. |
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