WEI Pengxiang,CHEN Xu,AI Quanshan.The clinical research on fractionated irradiation treatment with X knife in patients of PD[J].Chinese Journal of Radiological Medicine and Protection,2003,23(4):280-282 |
The clinical research on fractionated irradiation treatment with X knife in patients of PD |
Received:April 09, 2003 |
DOI: |
KeyWords:SRNS X knife FIT PD |
FundProject:解放军科研基金资助项目(2000);吉林省卫生厅基金资助项目(1998) |
Author Name | Affiliation | WEI Pengxiang | Department of Neurosurgery, Beijing Friendship Hospital, Beijing 100050, China | CHEN Xu | Department of Neurosurgery, Beijing Friendship Hospital, Beijing 100050, China | AI Quanshan | Department of Neurosurgery, Beijing Friendship Hospital, Beijing 100050, China | 夏吉勇 | Department of Neurosurgery, Beijing Friendship Hospital, Beijing 100050, China | 杨炯达 | 北京天坛医院神经外科 | 陈炳桓 | 北京天坛医院神经外科 |
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Abstract:: |
Objective To explore X knife treatment methods and to seek a new effective way for PD therapy. Methods Sixteen patients of PD were treated by performing VIM with 2 times of X knife fractionated irradiation (interval, 24 h) to a total dose of 140 Gy, and 8 patients of PD were treated by performing VIM with 3 times of X knife fractionated irradiation (interval, 24 h) to a total of dose of 165 Gy. Results During 3-24 months follow-up after X knife treatment, tremor was stopped in 19 patients and was relived significantly in 5 patients. Rigidity and bradykinesia of PD were relieved slightly. No complications were observed. Conclusion To perform VIM with X knife fractionated irradiation can be safely and effectively used to treat PD. The tremor of PD can be relieved slightly. |
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