WEI Pengxiang,CHEN Xu,AI Quanshan.The clinical research on fractionated irradiation treatment with X knife in patients of PD[J].Chinese Journal of Radiological Medicine and Protection,2003,23(4):280-282
The clinical research on fractionated irradiation treatment with X knife in patients of PD
Received:April 09, 2003  
DOI:
KeyWords:SRNS  X knife  FIT  PD
FundProject:解放军科研基金资助项目(2000);吉林省卫生厅基金资助项目(1998)
Author NameAffiliation
WEI Pengxiang Department of Neurosurgery, Beijing Friendship Hospital, Beijing 100050, China 
CHEN Xu Department of Neurosurgery, Beijing Friendship Hospital, Beijing 100050, China 
AI Quanshan Department of Neurosurgery, Beijing Friendship Hospital, Beijing 100050, China 
夏吉勇 Department of Neurosurgery, Beijing Friendship Hospital, Beijing 100050, China 
杨炯达 北京天坛医院神经外科 
陈炳桓 北京天坛医院神经外科 
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Abstract::
      Objective To explore X knife treatment methods and to seek a new effective way for PD therapy. Methods Sixteen patients of PD were treated by performing VIM with 2 times of X knife fractionated irradiation (interval, 24 h) to a total dose of 140 Gy, and 8 patients of PD were treated by performing VIM with 3 times of X knife fractionated irradiation (interval, 24 h) to a total of dose of 165 Gy. Results During 3-24 months follow-up after X knife treatment, tremor was stopped in 19 patients and was relived significantly in 5 patients. Rigidity and bradykinesia of PD were relieved slightly. No complications were observed. Conclusion To perform VIM with X knife fractionated irradiation can be safely and effectively used to treat PD. The tremor of PD can be relieved slightly.
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