| CHEN Jinsheng,JIANG Yuanshi,CAO Xibiao.Correlative study on anemia and radiotherapy effects in nasopharyngeal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2003,23(4):265-267 |
| Correlative study on anemia and radiotherapy effects in nasopharyngeal carcinoma |
| Received:December 25, 2002 |
| DOI： |
| KeyWords:Nasophanyngeal neplasms Radiotherapy Anemia Therapactia |
| FundProject:广东省科委重点科技攻关项目(97114);广东省卫生系统“五个一工程”重点专科基金资助项目(96186) |
| Author Name | Affiliation | | CHEN Jinsheng | Department of Otorhinolaryngology, Chaozhou Central Hospital, Chaozhou 521021, China | | JIANG Yuanshi | Department of Otorhinolaryngology, Chaozhou Central Hospital, Chaozhou 521021, China | | CAO Xibiao | Department of Otorhinolaryngology, Chaozhou Central Hospital, Chaozhou 521021, China | | 詹永忠 | Department of Otorhinolaryngology, Chaozhou Central Hospital, Chaozhou 521021, China | | 杨立业 | Department of Otorhinolaryngology, Chaozhou Central Hospital, Chaozhou 521021, China | | 陈建秀 | Department of Otorhinolaryngology, Chaozhou Central Hospital, Chaozhou 521021, China | | 陈成武 | Department of Otorhinolaryngology, Chaozhou Central Hospital, Chaozhou 521021, China | | 李杨 | Department of Otorhinolaryngology, Chaozhou Central Hospital, Chaozhou 521021, China |
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| Abstract:: |
| Objective To study the effect of oxygen-carrying ability of blood efficacy of radiotherapy for patients with nasopharyngeal carcinoma. Methods Altogether 161 cases of patients with nasopharyngeal carcinoma were classified according to severity of anemia, and Hb, RBC, MCH, HCT, MCV, MCHC and RDW were tested before, during and after radiotherapy.The patients were followed-up for up to 5 years, the relationship and mechanism among anemia, radiotherapy effects and survival rate was discussed. Results The survival rate between anemia group and non-anemia group was different significantly (PP<0.05) . Anemia before radiotherapy, anemia appearance or anemia deterioration during radiotherapy were sensitive factors affecting radiotherapy results.The anemia more severe, the radiotherapy worse. Conclusion Anemia-hypohemoglobinemia leads to decrease of oxygen-carrying capacity of blood, resalting in oxygen deficiency of tumor cells and their radiotherapy resistance, Therefore this method is worthy of further studies. |
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