| LÜ Huimin,DONG Jinchan,ZHANG Cuilan.DNA damage in peripheral blood lymphocytes of residents with radon exposure in indoor[J].Chinese Journal of Radiological Medicine and Protection,2002,22(5):340-342 |
| DNA damage in peripheral blood lymphocytes of residents with radon exposure in indoor |
| Received:December 25, 2001 |
| DOI： |
| KeyWords:Radon DNA damage Single cell gel electrophoresis Micronucleus |
| FundProject:国家自然科学基金资助项目(39470842) |
| Author Name | Affiliation | | LÜ Huimin | Institute for Radiological Protection and Nuclear Safty, China CDC, Beijing 100088, China | | DONG Jinchan | Institute for Radiological Protection and Nuclear Safty, China CDC, Beijing 100088, China | | ZHANG Cuilan | Institute for Radiological Protection and Nuclear Safty, China CDC, Beijing 100088, China | | 张守志 | Institute for Radiological Protection and Nuclear Safty, China CDC, Beijing 100088, China |
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| Abstract:: |
| Objective To determine the damage of DNA in peripheral blood lymphocytes samples from resident exposure to radon in indoor air. Methods Single cell gel electrophoresis and micronucleus measure methods were used in the present study. Results The results of cell migration frequencies for residents in cave dwellings and normal houses were shown 1.68% and 1.43%,of calculation by residents were 57. 1% and 54 3% respectively.The frequencies of micronucleus results for residents of cave dwellings and normal houses were 1. 07% and 0.78% respectively. Conclusion The frequencies of DNA damage and the ratio of micronucleus for residents living in cave dwellings was shown some higher than that of residents living in normal houses, p values close to 0. 05. |
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