ZHANG Wei,WANG Jixian,ZHAO Yongcheng.Risk factors of hypertension among medical diagnostic X-ray workers in China[J].Chinese Journal of Radiological Medicine and Protection,2002,22(4):246-249 |
Risk factors of hypertension among medical diagnostic X-ray workers in China |
Received:June 15, 2001 |
DOI: |
KeyWords:Medical diagnostic X-ray workder Essential hypertension onizing radiation Risk factors Case-control study |
FundProject:日本体质研究会基金资助项目 |
Author Name | Affiliation | ZHANG Wei | Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192, China | WANG Jixian | Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192, China | ZHAO Yongcheng | Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192, China | 李本孝 | Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192, China | 樊体强 | Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192, China |
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Abstract:: |
Objective To investigate the risk factors of essential hypertension in medical diagnostic X-ray workers in China, especially for the relationship between essential hypertension and occupational irradiation. Methods A 1:2 matched case-control study was carried out.The study subjects consisted of 288 pairs of matched cases and controls coming from different hospitals in China.Information about occupational and non-occupational risk factors were obtained through questionnaire.Individual doses were estimated by normalized workload method.Conditional Logistic regression method was applied to data analysis with SAS6.12 software. Results Variables such as overweight (OR=3.087, P =0.001), family history of hypertension (OR=3.140, P =0.001), worring about X-ray work as a health-damaging occupation (OR=1 798, P =0.010) were three main risk factors in the ungrouped data.Dividing the study subjects into different subgroups according to sex and calendar period of entry, the highest level of accumulated dose (>300 mGy) as a risk factor had statistically reached significant level in the male X-ray workers of the earlier period of entry (OR=5.672, P =0.22). Conclusion For medical diagnostic X-ray workers, overweight, family history of hypertension and occupational stress are the main risk factors of essential hypertension.For those accumulated doses over 300 mGy, indicating ionizing radiation may be a potential risk factor.As there is no reasonable biological mechanism to explain these findings, further studies are needed. |
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