.Clinical studies of effect of Jinshi Granule on reducing the toxic radiotherapy reaction in nasopharyngeal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2002,22(1):42-43
Clinical studies of effect of Jinshi Granule on reducing the toxic radiotherapy reaction in nasopharyngeal carcinoma
Received:April 24, 2001  
DOI:
KeyWords:Jinshi Granule  Nasopharyngeal carcinoma  Toxic reaction of radiotherapy  
FundProject:山东省科委重点基金资助项目(951197502)
Author NameAffiliation
范士怀 276001 山东, 临沂市肿瘤医院 
贺方学 276001 山东, 临沂市肿瘤医院 
葛来增 276001 山东, 临沂市肿瘤医院 
申源峰 276001 山东, 临沂市肿瘤医院 
吕相坤 276001 山东, 临沂市肿瘤医院 
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Abstract::
      Objective To study the effects of Jinshi Granule (JSG) on decreasing the toxic reaction of radiotherapy in nasopharyngeal carcinoma (NPC) patients in order to search for an effective method and medicines. Methods Altogether 90 patients with NPC treated by radical radiotherapy were divided into three groups at random. Each group consisted of 30 patients who all received radiotherapy.Patients of the 1st treatment group were treated by JSG, the 2nd treatment group by Biyan Qingdu Ji(BQJ), and the control group by placebo. Results ①In JSG group, the effective rate, the rate of completing radiotherapy, the enhancing and stabilization rate of quality of life were 93.33%, 96.67%, and 90.00%, respectively, which were all higher than those in other groups(P<0.05, P<0.01).②The degree of the toxic reaction syndromes in the JSG group was lower than that in other two groups and the stabilization of peripheral hemogram was much better (P<0.05, P<0.01). Conclusion These data show that JSG has significant effects on reducing the toxic reaction of radiotherapy to NPC and combining it with radiotherapy is an effective method in treating NPC.
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