QIN Ling,CHEN Jiaxin,ZHANG Lixiang.Study on change of multimodally evoked potentials in nasopharyngeal carcinoma patients after radiotherapy[J].Chinese Journal of Radiological Medicine and Protection,2001,21(4):301-304
Study on change of multimodally evoked potentials in nasopharyngeal carcinoma patients after radiotherapy
Received:August 29, 2000  
DOI:
KeyWords:Nasopharyngeal carcinoma  Radiation-injury  Evoked potential
FundProject:广西壮族自治区科研研究与技术开发计划资助项目(9631062)
Author NameAffiliation
QIN Ling The People's Hospital of Guangxi Zhuang Nationality Autonomous Region, Nanning 530021, China 
CHEN Jiaxin 广西壮族自治区人民医院肌电诱发电位室 
ZHANG Lixiang 广西壮族自治区人民医院放疗科 
王铁建 The People's Hospital of Guangxi Zhuang Nationality Autonomous Region, Nanning 530021, China 
韩敏 The People's Hospital of Guangxi Zhuang Nationality Autonomous Region, Nanning 530021, China 
卢晓玲 广西壮族自治区人民医院肌电诱发电位室 
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Abstract::
      Objective To investigate possible changes of multimodally evoked potentials in nasopharyngeal carcinoma patients after radiotherapy. Methods Altogether 48 nasopharyngeal carcinoma patiens receiving primary conventional external beam irradiation were examined before and after radiotherapy to determine their brainstem auditory-evoked potential(BAEP),short-latency somatosensory-evoked potential(SLSEP)and pattern reversal visual-evoked potential(PRVEP). Results In comparion with the conditions before radiotherapy,in different periods after radiotherapy abnormal peak latency and interval latency difference were found in BAEP,SLSEP and PRVEP. Conclusion Nasopharyngeal carcinoma after radiotheray may cause abnormal function of nerve conduction in early periods,which can be showed by BAEP,SLSEP,PRVEP,and injury can be timely detected if the three evoked potentials are used together.Thus we suggest BAEP,SLSEP,PRVEP should be examined in nasopharyngeal carcinoma patients during and after the radiotherapy so as to find early damage in auditory somatosensory and visual conduction pathways.
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