CHEN Jianwei,HUANG Gang,LI Shijun.Calculation of absorbed dose of anchorage-dependent cells from internal beta-rays irradiation[J].Chinese Journal of Radiological Medicine and Protection,2001,21(4):250-252
Calculation of absorbed dose of anchorage-dependent cells from internal beta-rays irradiation
Received:April 30, 2001  
DOI:
KeyWords:Absorbed dose  Beta-rays  Irradiation
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Author NameAffiliation
CHEN Jianwei Department of Nuclear Medicine, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China 
HUANG Gang Department of Nuclear Medicine, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China 
LI Shijun 苏州大学核医学院 
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Abstract::
      Objective To elicit the formula of internal dosimetry in anchorage-dependent cells by beta-emitting radionuclides from uniformly distributed volume sources. Methods By means of the definition of absorbed dose and the MIRD(Medical International Radiation Dose) scheme the formula of internal dosimetry was reasonably deduced.Firstly,studying the systems of suspension culture cells.Then,taking account of the speciality of the systems of the anchorage-dependent cells and the directions of irradiation,the absorbed dose of anchorage-dependent cells was calculated by the accumulated radioactivity,beta-ray energy,and the volume of the cultured systems. Results The formula of internal dosimetry of suspension culture cells and anchorage-dependent cells were achieved.At the same time,the formula of internal dosimetry of suspension culture cells was compared with that of MIRD and was confirmed accurate. Conclusion The formula of internal dosimetry is concise,reliable and accurate.
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