| SUN Suping,CAI Jianming,XIANG Yingsong.Homing regularity of different doses bone marrow transplantation in allogeneic hosts[J].Chinese Journal of Radiological Medicine and Protection,2001,21(2):87-89 |
| Homing regularity of different doses bone marrow transplantation in allogeneic hosts |
| Received:May 20, 2000 |
| DOI： |
| KeyWords:Allogeneic mouse Bone marrow transplantation Homing Homing efficiency |
| FundProject:国家自然科学基金资助项目(39770329,3960077) |
| Author Name | Affiliation | | SUN Suping | Department of Radiation Medicine, Second Military Medical University, Shanghai 200433, China | | CAI Jianming | Department of Radiation Medicine, Second Military Medical University, Shanghai 200433, China | | XIANG Yingsong | Department of Radiation Medicine, Second Military Medical University, Shanghai 200433, China | | 赵芳 | Department of Radiation Medicine, Second Military Medical University, Shanghai 200433, China | | 黄定德 | Department of Radiation Medicine, Second Military Medical University, Shanghai 200433, China | | 高建国 | Department of Radiation Medicine, Second Military Medical University, Shanghai 200433, China | | 杨如俊 | Department of Radiation Medicine, Second Military Medical University, Shanghai 200433, China |
|
| Hits: 2514 |
| Download times: 2137 |
| Abstract:: |
| Objective To explore the homing regularity of different doses of bone marrow cell transplantation.Method An allogeneic mouse model was used in this study.The homing status of different dose groups from the first day to the forth day after transplantation were observed.Results The rate of positive cells in bone marrow and spleen:differences among four groups was not significant.The rate of positive cells of third day was highest among four days ( P <0.01).A phenomenon that homing-mobilization-rehoming could be observed.The homing efficiency:low dose groups were higher than that high dose groups ( P <0.01).Conclusion The homing efficiency of low dose groups is higher than that of the high dose groups in certain range,the routine method of transplanting a large quantities cells by a single injection may be an waste. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
